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Merck

PHR1191

Supelco

Nitrofurantoin

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

N-(5-Nitro-2-furfurylidene)-1-aminohydantoin, Furadoxyl, Nitrofurantoine

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C8H6N4O5
CAS 번호:
67-20-9
Molecular Weight:
238.16
Beilstein:
893207
EC Number:
200-646-5
MDL number:
MFCD00003224
UNSPSC 코드:
41116107
PubChem Substance ID:
329823199
NACRES:
NA.24

주요 문서

모든 문서 보기
기술 서비스
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도움 문의
기술 서비스
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도움 문의

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1464001

API family

nitrofurantoin

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1

InChI

1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+

InChI key

NXFQHRVNIOXGAQ-YCRREMRBSA-N

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관련 카테고리

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Nitrofurantoin, a synthetic, nitrofuran-derivative, is a widely used urinary antimicrobial compound that is effective against pulmonary fibrosis, neuropathy, hepatitis and hemolytic anemia.

애플리케이션

Nitrofurantoin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by voltammetry and chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9007 in the slot below. This is an example certificate only and may not be the lot that you receive.

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Danger

유해 및 위험 성명서

H302,H317,H334

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Stripping voltammetric behaviour of toxic drug nitrofurantoin
Jain R, et al.
Journal of Hazardous Materials, 169(1-3), 667-672 (2009)
Liquid chromatographic and spectrophotometric determination of phenazopyridine hydrochloride, ampicilline trihydrate, and nitrofurantoine in pharmaceutical preparations
Palabiyik IM and Onur F
Analytical Letters, 37(10), 2125-2150 (2004)
Determination of nitrofurantoin drug in pharmaceutical formulation and biological fluids by square-wave cathodic adsorptive stripping voltammetry
Hammam E
Journal of Pharmaceutical and Biomedical Analysis, 30(3), 651-659 (2002)
Detection of ampicillin contamination in nitrofurantoin preparations by high pressure liquid chromatography
Bracey A
Journal of Pharmaceutical Sciences, 62(10), 1695-1696 (1973)
Brenda M Kazemier et al.
BMC pregnancy and childbirth, 12, 52-52 (2012-08-16)
The prevalence of asymptomatic bacteriuria (ASB) in pregnancy is 2-10% and is associated with both maternal and neonatal adverse outcomes as pyelonephritis and preterm delivery. Antibiotic treatment is reported to decrease these adverse outcomes although the existing evidence is of
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