PHR1168
Ofloxacin
Pharmaceutical Secondary Standard; Certified Reference Material
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C18H20FN3O4
CAS 번호:
Molecular Weight:
361.37
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
Grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1478108
API family
ofloxacin, ofloxacin
CofA
current certificate can be downloaded
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-30°C
SMILES string
Fc1cc2c3[n](cc([c]2=O)C(=O)O)C(COc3c1N4CCN(CC4)C)C
InChI
1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChI key
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Ofloxacin is an orally administered antimicrobial drug that is classified under the group of fluoroquinolones. It has high potency and shows a broad-spectrum antibacterial performance, as well as short selection of resistant bacteria.
Ofloxacin is an orally administered antimicrobial drug that is classified under the group of fluoroquinolones. It has high potency and shows a broad-spectrum antibacterial performance, as well as short selection of resistant bacteria.
애플리케이션
Ofloxacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and serum samples by chromatography and spectrophotometry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
분석 메모
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
기타 정보
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7180 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Determination of Ofloxacin in Pharmaceutical Forms by High-Performance Liquid Chromatography and Derivative Uvspectrophotometry
Carlucci G, et al.
Analytical Letters, 26(10), 2193-2201 (1993)
Determination of ofloxacin in tear by HPLC-ESI-MS/MS method: Comparison of ophthalmic drug release between a new mucoadhesive chitosan films and a conventional eye drop formulation in rabbit model
Byrro RMD, et al.
Journal of Pharmaceutical and Biomedical Analysis, 70(5), 544-548 (2012)
Simultaneous determination of ofloxacin and flavoxate hydrochloride by absorption ratio and second derivative UV spectrophotometry
Attimarad M
Journal of Basic and Clinical Pharmacy, 2(1), 53-53 (2010)
Cécile Denève et al.
Antimicrobial agents and chemotherapy, 53(12), 5155-5162 (2009-10-07)
Recent outbreaks of Clostridium difficile infection have been related to the emergence of the NAP1/027 epidemic strain. This strain demonstrates increased virulence and resistance to the C-8-methoxyfluoroquinolones gatifloxacin and moxifloxacin. These antibiotics have been implicated as major C. difficile infection-inducing
J Kawakami et al.
Journal of pharmacokinetics and biopharmaceutics, 22(3), 207-227 (1994-06-01)
We attempted to predict the delivery of ofloxacin (OFLX), a new quinolone antibacterial agent (NQ), into cerebrospinal fluid (CSF) in the human based on the physiological properties and pharmacokinetic parameters of NQs in various animals. Physiological properties for evaluation of
문서
LC-MS/MS-based determination of 19 sulfonamides, 13 quinolones, and 3 tetracycline drug residues in pork meat samples using Supel™ Swift HLB for extraction.
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