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Merck

PHR1057

Supelco

Furosemide

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

FUR, 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid, 5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C12H11ClN2O5S
CAS 번호:
54-31-9
Molecular Weight:
330.74
EC Number:
200-203-6
MDL number:
MFCD00010549
UNSPSC 코드:
41116107
PubChem Substance ID:
329823087
NACRES:
NA.24

주요 문서

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기술 서비스
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도움 문의

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. F0700000
traceable to USP 1287008

API family

furosemide

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

mp

220 °C (dec.) (lit.)

응용 분야

forensics and toxicology
pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl

InChI

1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)

InChI key

ZZUFCTLCJUWOSV-UHFFFAOYSA-N

유전자 정보

human ... SLC12A1(6557)

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관련 카테고리

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Furosemide is a diuretic drug, which finds a variety of therapeutic applications such as hepatic cirrhosis, cardiac insufficiency and arterial hypertension.

애플리케이션

Furosemide may also be used as a reference standard in determining the concentration of furosemide present in human urine samples using gas chromatography coupled with mass spectrometry (GC-MS). Furosemide may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using diffuse reflectance spectroscopy.
Furosemide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry, spectrophotometry and high performance liquid chromatography (HPLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

생화학적/생리학적 작용

Inhibits ion co-transport in the kidney.

분석 메모

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

기타 정보

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7130 in the slot below. This is an example certificate only and may not be the lot that you receive.

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Danger

유해 및 위험 성명서

H302,H360FD

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Sensitive micro analysis of frusemide (furosemide) in bulk drug and formulations by visible spectrophotometry and high performance liquid chromatography (HPLC)
Basavaiah K and Chandrashekar U
Indian Journal of Chemical Technology, 249(1), 117-126 (2005)
Determination of furosemide in pharmaceutical formulations by diffuse reflectance spectroscopy
Gotardo AM, et al.
Talanta, 64(2), 361-365 (2004)
A novel application of immobilization on membranes for the separation and spectrofluorimetric quantification of amiloride and furosemide in pharmaceutical samples
MCP, et al.
Analytica Chimica Acta, 661(1), 85-90 (2010)
Simultaneous determination of amiloride and furosemide in pharmaceutical formulations by first digital derivative spectrophotometry
Toral MI, et al.
International Journal of Pharmaceutics, 249(1), 117-126 (2002)
Simultaneous Determination of the Diuretics Triamterene and Furosemide in Pharmaceutical Formulations and Urine by HPLC-EC
Barroso MB, et al.
Journal of Liquid Chromatography and Related Technologies, 19(2), 231-246 (1996)
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