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Merck

SCC034

Sigma-Aldrich

Human Mesenchymal Stem Cells (Bone Marrow)

Human mesenchymal stem cells derived from bone marrow that have a capacity for expansion in vitro while maintaining their potential for differentiation to multiple lineages including adipocytes, osteoblasts and chondrocytes.

동의어(들):

Human Bone Marrow MSCs, Human Bone Marrow Multipotent Stem Cells, Human MSCs

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

UNSPSC 코드:
41106509
eCl@ss:
32011203
NACRES:
NA.75

주요 문서

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기술 서비스
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기술 서비스
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도움 문의

생물학적 소스

human

Quality Level

100

기술

cell culture | mammalian: suitable
cell culture | stem cell: suitable
cell differentiation: suitable

입력

sample type mesenchymal stem cell(s)

배송 상태

liquid nitrogen

관련 카테고리

일반 설명

Mesenchymal stem cells, also known as marrow stromal cells, are defined as a self-renewing population of adherent, bone-marrow-derived multipotent progenitor cells with the capacity to differentiate into several mesenchymal cell lineages. In defined cultures in vitro, mesenchymal stem cells have been shown to readily differentiate into lineage-specific cells that form bone, cartilage, fat, tendon, and muscle tissues.

EMD Millipore’s Human Mesenchymal Stem Cells (Bone Marrow) are isolated from normal human bone marrow and are cryopreserved at P2 to ensure optimal phenotype and the highest viability and plating efficiency. These cells proliferate as an adherent cell monolayer and have shown a strong capacity for expansion in vitro while maintaining their potential for differentiation to multiple lineages including adipocytes, osteoblasts and chondrocytes..

애플리케이션

Research Category
Stem Cell Research

생화학적/생리학적 작용

Mesenchymal Stem Cells

제조 메모

Human Mesenchymal Stem Cells (Bone Marrow) should be stored in liquid nitrogen. The cells are guaranteed for at least 3 population doublings without significantly affecting cell surface marker expression and differentiation potential.

분석 메모

- Each vial contains at least 1X10⁶ viable cells at P2.
- Cell viability is greater than 75% at thaw and cells can be cultured for at least 3 population doublings after the initial thaw.
- Bone marrow donors tested negative for HIV, hepatitis B and hepatitis C.
- Apparently normal karyotype per cytogenetic analysis.
- Cells tested negative for mycoplasma contamination.

기타 정보

1X106 viable Human Bone Marrow Mesenchymal Stem Cells

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Diego Omar Sanchez Ramirez et al.
Bioengineering (Basel, Switzerland), 8(12) (2021-12-24)
Protein-based nanofibres are commonly used in the biomedical field to support cell growth. For this study, the cell viability of wool keratin-based nanofibres was tested. Membranes were obtained by electrospinning using formic acid, hexafluoroisopropanol, and water as solvents. For aqueous
Christy Wing Tung Wong et al.
Stem cell research & therapy, 13(1), 419-419 (2022-08-14)
Critical limb ischemia (CLI) is the most severe form of peripheral artery disease and exhibits a high risk of lower extremity amputations. As even the most promising experimental approaches based on mesenchymal stem cells (MSCs) demonstrated only moderate therapeutic effects
LncRNA-NEF is downregulated in postmenopausal osteoporosis and is related to course of treatment and recurrence.
Xiaoyong Ma et al.
The Journal of international medical research, 47(7), 3299-3306 (2019-06-22)
Adam R Wolfe et al.
Oncotarget, 7(50), 82482-82492 (2016-10-21)
Inflammatory breast cancer (IBC) is a unique and deadly disease with unknown drivers. We hypothesized the inflammatory environment contributes to the IBC phenotype. We used an in vitro co-culture system to investigate interactions between normal and polarized macrophages (RAW 264.7
Edo Dzafic et al.
BioMed research international, 2014, 508216-508216 (2014-04-12)
After removal of oocytes for in vitro fertilization, follicular aspirates which are rich in somatic follicular cells are discarded in daily medical practice. However, there is some evidence that less differentiated cells with stem cell characteristics are present among aspirated
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문서

Mesenchymal Stem Cell Culture

Highly characterized human mesenchymal stem cell lines from bone-marrow, adipose and umbilical cord along with serum-free MSC expansion and differentiation media.

Mesenchymal Stem Cell FAQs

Frequently asked questions about mesenchymal stem cells including MSC derivation, expansion, differentiation and allogenic stem cell therapy.

Accelerated Osteocyte Differentiation of Human Mesenchymal Stem Cells in a Novel Xeno-free and Serum-free Osteogenesis Differentiation Media

Development of a novel serum-free and xeno-free human mesenchymal stem cell (MSC) osteocyte differentiation media.

PLTMax® Human Platelet Lysate (hPL): A Superior Serum-Free Media Supplement for Robust Mesenchymal Stem Cell Expansion

PLTMax® Human Platelet Lysate (hPL) is a superior serum-free and xeno-free media supplement alternative to fetal bovine serum (FBS) for human mesenchymal stem cell (MSC) cultures.

모두 보기

프로토콜

Mesenchymal Stem Cell Culture Protocols

Information about mesenchyme, specifically mesenchymal stem cell procotols. Step-by-step cell culture protocols for mesenchymal stem cell (MSC) isolation, expansion and differentiation.

관련 콘텐츠

A Novel Serum-free and Xeno-free Differentiation Medium for Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells

We have collaborated with Plasticell Ltd. to develop OsteoMAX-XF™, a novel, serum-free, xeno-free, differentiation medium for the generation of osteoblasts from human MSCs. This medium may be particularly suitable for drug discovery and clinical development. By screening roughly 3,500 combinations of serum and xeno-free media, we discovered a remarkably efficient, fully defined, reproducible medium to promote the differentiation of hMSCs into osteoblasts, offering an excellent, cost effective method to produce large amounts of human bone cells for multiple applications.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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