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Merck

MAB3402

Sigma-Aldrich

Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5

clone GA5, Chemicon®, from mouse

동의어(들):

GFAP

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

주요 문서

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기술 서비스
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도움 문의
기술 서비스
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도움 문의

생물학적 소스

mouse

Quality Level

100

결합

unconjugated

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

GA5, monoclonal

종 반응성

chicken, pig, rat, bovine, mouse, rabbit, human

제조업체/상표

Chemicon®

기술

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

동형

IgG1

NCBI 수납 번호

XP_005668766.1

UniProt 수납 번호

F1RR02

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... GFAP(2670)

일반 설명

50 kDa
Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.

면역원

Purified Glial Fibrillary Acidic Protein (GFAP) from pig spinal cord (Debus, E., 1983).

애플리케이션

Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5 is an antibody against Glial Fibrillary Acidic Protein for use in IC, IH, IH(P) & WB with more than 55 product citations.
Immunocytochemistry:
5 μg/mL of a previous lot was used.

Immunohistochemistry:
5 µg/mL

Immunoblotting:
Recognizes a 51kDa protein in reducing westerns of total brain lysates.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

생화학적/생리학적 작용

Expected to cross-react with porcine, chicken, bovine, and rabbit.
The antibody reacts with GFAP from human, pig, chicken and rat. In tissue sections this antibody stains astrocytes and Bergman glia cells (Debus, E., 1983).

물리적 형태

Format: Purified
Protein A purified
Purified mouse monoclonal IgG1 in buffer containing 0.02 M phosphate buffer, 0.25 M NaCl with 0.1% sodium azide, pH 7.6.

제조 메모

Store the reconstituted antibody at 2-8°C for up to 6 months after date of receipt.
DO NOT FREEZE.

분석 메모

Control
Mouse brain tissue, Astrocyte culture.
Routinely evaluated by Western Blot on Mouse brain lysate.

Western Blot Analysis:
1:1000 dilution of this lot detected Glial Fibrillary Acidic Protein on 10 μg of Mouse Brain lysate.

기타 정보

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Replaces: 04-1031; 04-1062

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

D Ballhausen et al.
Neuroscience, 164(2), 578-587 (2009-08-25)
Methylmalonyl-CoA mutase (MCM) and propionyl-CoA carboxylase (PCC) are the key enzymes of the catabolic pathway of propionate metabolism and are mainly expressed in liver, kidney and heart. Deficiency of these enzymes leads to two classical organic acidurias: methylmalonic and propionic
Proliferation inhibition, DNA damage, and cell-cycle arrest of human astrocytoma cells after acrylamide exposure.
Chen JH, Tsou TC, Chiu IM, Chou CC
Chemical Research in Toxicology null
Alteration of glial-neuronal metabolic interactions in a mouse model of Alexander disease.
Meisingset, TW; Risa, ?; Brenner, M; Messing, A; Sonnewald, U
Glia null
T Nishio et al.
Neuroscience, 132(1), 87-102 (2005-03-23)
Tenascin-C (TNC), an extracellular matrix glycoprotein, is involved in tissue morphogenesis like embryogenesis, wound healing or tumorigenesis. Astrocytes are known to play major roles in wound healing in the CNS. To elucidate the roles of TNC in wound closure by
Selective removal of photoreceptor cells in vivo using the biodegradable elastomer poly(glycerol sebacate).
Ghosh, F; Neeley, WL; Arner, K; Langer, R
Tissue Engineering: Part A null
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관련 콘텐츠

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