MAB2259Z
Anti-Integrin β1 Antibody, activated, clone B44, azide free
clone B44, Chemicon®, from mouse
동의어(들):
Ligand-inducedBindingSite, LIBS, CLIBS, MAB2259
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
B44, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
cell culture | mammalian: suitable
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... ITGB1(3688)
관련 카테고리
일반 설명
88 kDa
애플리케이션
Immunoprecipitation of detergent-solubilized (1 integrins: 2-4 μg/IP
Western blot: 10-15 μg/mL
Flow Cytometry: 10-15 μg/mL
Immunohistochemistry
Stimulation of (1-mediated adhesion: 10-20 μg/mL.
Optimal working dilutions must be determined by end user.
Western blot: 10-15 μg/mL
Flow Cytometry: 10-15 μg/mL
Immunohistochemistry
Stimulation of (1-mediated adhesion: 10-20 μg/mL.
Optimal working dilutions must be determined by end user.
This Anti-Integrin β1 Antibody, activated, clone B44, azide free is validated for use in FC, IH, IP, FUNC, CULT, WB for the detection of Integrin β1.
생화학적/생리학적 작용
Detects a cation- and ligand-induced binding site (LIBS) of integrin beta 1, which has been used in some systems as a reporter of integrin functionality.
물리적 형태
Format: Purified
Purified immunoglobulin. Liquid PBS, containing no preservatives.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Induction of type XVI collagen expression facilitates proliferation of oral cancer cells.
Sabine Ratzinger,Susanne Grassel,Albert Dowejko,Torsten E Reichert,Richard J Bauer
Matrix Biology null
Are changes in integrin affinity and conformation overemphasized? REVIEW
Bazzoni G. and Hemler M.
Trends in Biochemical Sciences, 23, 30-34 (1998)
M Levite et al.
The Journal of experimental medicine, 191(7), 1167-1176 (2000-04-05)
Elevated extracellular K(+) ([K(+)](o)), in the absence of "classical" immunological stimulatory signals, was found to itself be a sufficient stimulus to activate T cell beta1 integrin moieties, and to induce integrin-mediated adhesion and migration. Gating of T cell voltage-gated K(+)
Weisheng Wang et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 41(11), 2723-2732 (2016-06-09)
Estradiol (E2) perfusion rapidly increases the strength of fast excitatory transmission and facilitates long-term potentiation in the hippocampus, two effects likely related to its memory-enhancing properties. Past studies showed that E2's facilitation of transmission involves activation of RhoA signaling leading
Tommy Hui et al.
Matrix biology : journal of the International Society for Matrix Biology, 41, 19-25 (2014-12-03)
Osteopontin (OPN) is a ligand for the α4ß1 integrin, but the physiological importance of this binding is not well understood. Here, we have assessed the effect of post-translational modifications on OPN binding to the α4 integrin on cultured human leukocyte
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