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Merck

AB5977

Sigma-Aldrich

Anti-Musashi-1 Antibody

Chemicon®, from rabbit

동의어(들):

Musashi homolog 1

로그인조직 및 계약 가격 보기

크기 선택

제품정보 (DICE 배송 시 비용 별도)

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

주요 문서

모든 문서 보기
기술 서비스
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도움 문의
기술 서비스
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도움 문의

생물학적 소스

rabbit

Quality Level

100

결합

unconjugated

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

rodent, mouse, rat, human

제조업체/상표

Chemicon®

기술

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI 수납 번호

NM_002442.2

UniProt 수납 번호

O43347

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... MSI1(4440)

일반 설명

39 kDa
In mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, differentiation and tumorigenesis. Musashi1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi1 is a selective marker for intestinal stem or early lineage cells. Musashi1 interacts with the Notch pathway during asymmetric cell division by binding the 3′ UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi1 is present.

면역원

Synthetic peptide, amino acids 5-21 of Musashi.

애플리케이션

Detect Musashi-1 using this Anti-Musashi-1 Antibody validated for use in IC, IH & WB.
Immunohistochemistry:
1:200-1:1,000 dilution from a previous lot was used.

Immunocytochemistry:
1:200-1:1,000 dilution from a previous lot was used.

Western blot:
1:200-1:1,000 using ECL.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Developmental Neuroscience

RNA Binding Protein (RBP)

생화학적/생리학적 작용

Reactivity with other species has not been confirmed.
Recognizes Musashi-1.

물리적 형태

ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

제조 메모

Stable for 1 year at -80ºC from date of receipt.

분석 메모

Control
Mouse cortical neural stem cells (Catalog No. SCR029).
Routinely evaluated by Western Blot on Human Placenta lysates.

Western Blot Analysis:
1:1000 dilution of this lot detected Musashi-1 on 10 μg of Human placenta lysates.

기타 정보

Replaces: 03-114; 04-1041

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Long-term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions
Shin, Soojung, et al.
Stem Cells, 24, 125-138 (2006)
Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration.
Gonzalez, LM; Williamson, I; Piedrahita, JA; Blikslager, AT; Magness, ST
Testing null
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice
Maslov, Alexander Y, et al.
The Journal of Neuroscience, 24, 1726-1733 (2004)
Postnatal epithelial growth of the small intestine in the rat occurs by both crypt fission and crypt hyperplasia.
Adrian G Cummins, Ben J Jones, Fiona M Thompson
Digestive Diseases and Sciences null
Raffaella Scardigli et al.
Stem cells (Dayton, Ohio), 32(9), 2516-2528 (2014-05-09)
Adult neurogenesis is a multistep process regulated by several extrinsic factors, including neurotrophins. Among them, little is known about the role of nerve growth factor (NGF) in the neurogenic niches of the mouse. Here we analyzed the biology of adult
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관련 콘텐츠

RNA-Binding Protein Immunoprecipitation

All eukaryotic organisms require tight regulation of gene expression for complex processes such as development, differentiation, cell specification, and responses to environmental stimuli. Many genes are regulated post-transcriptionally, in addition to transcriptional mechanisms of gene regulation. RNA-binding proteins (RBPs) are essential for post-transcriptional gene regulation, linking transcription and translation in many processes including transcription, splicing, export, rate of translation and turnover. In all of these events, RBPs coordinate regulation of the amount of protein produced from mRNA transcripts.

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