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8.17058

Maleic acid

EMPROVE® ESSENTIAL, Ph. Eur., NF

동의어(들):

cis-Butenedioic acid, Toxilic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
HO2CCH=CHCO2H
CAS 번호:
110-16-7
Molecular Weight:
116.07
EC Index Number:
203-742-5
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
605762
MDL number:
MFCD00063177
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도움 문의

Quality Level

500

agency

NF, Ph. Eur.

vapor pressure

<0.1 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

assay

99.0-101.0% substance (anhydrous) basis

form

solid

potency

708 mg/kg LD50, oral (Rat), 1560 mg/kg LD50, skin (Rabbit)

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

pH

1.3 (20 °C, 100 g/L in H2O)

mp

130-135 °C (lit.)

solubility

478.8 g/L

density

1.59 g/mL at 25 °C (lit.)

cation traces

Fe: ≤5 ppm, V: ≤1 ppm, heavy metals (as Pb): ≤10 ppm

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

OC(=O)\C=C/C(O)=O

InChI

1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1-

InChI key

VZCYOOQTPOCHFL-UPHRSURJSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Maleic acid is typically used as pH adjuster or buffer agent in pharmaceutical formulations. Maleic acid Emprove® Essential is mainly used in highly regulated pharmaceutical applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

target_organs

Respiratory system

저장 등급

8A - Combustible corrosive hazardous materials

wgk

WGK 1

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

시험 성적서(COA)

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