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Merck

05-1108

Anti-Insulin Antibody, clone1

clone MAB1, from mouse, purified by affinity chromatography

동의어(들):

Anti-IDDM, Anti-IDDM1, Anti-IDDM2, Anti-ILPR, Anti-IRDN, Anti-MODY10, Anti-PNDM4

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
MAB1, monoclonal
Application:
IHC
Citations:
1
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

MAB1, monoclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable (paraffin)

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... INS(3630)

General description

Approx. 12 kDa
Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, it has effects on fat metabolism.

Immunogen

Biosynthetic human insulin

Application

Anti-Insulin Antibody, clone1 is an antibody against Insulin for use in IH(P).
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Biochem/physiol Actions

This antibody recognizes an epitope including the amino acid B30.

Physical form

Affinity purified
The monoclonal is presented as 1mg in 1ml phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Preparation Note

Store at 2-8°C and use within 1 year from date of receipt.

Analysis Note

Control
Human pancreas tissue.
Evaluated by Immunohistochemistry in human pancreas tissue.
Immunohistochemistry Analysis: 1.25 µg/mL of this antibody detected insulin in human pancreas tissue.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: CBL71

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

저장 등급

12 - Non Combustible Liquids



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문서 라이브러리 방문



Gladys Teitelman
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 68(10), 691-702 (2020-10-02)
In pancreatic beta cells, proinsulin (ProIN) undergoes folding in endoplasmic reticulum/Golgi system and is translocated to secretory vesicles for processing into insulin and C-peptide by the proprotein convertases (PC)1/3 and PC2, and carboxypeptidase E. Human beta cells show significant variation