900408P
Avanti
pacFA-18:1 PC
Avanti Research™ - A Croda Brand
동의어(들):
1-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-2-oleoyl-sn-glycero-3-phosphocholine
제품 이름
pacFA-18:1 PC, Avanti Research™ - A Croda Brand 900408P, powder
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 1 mg (with stopper and crimp cap (900408P-1mg))
제조업체/상표
Avanti Research™ - A Croda Brand 900408P
지질 유형
click reagents
phospholipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
C#CCCCC1(N=N1)CCCCCCCCC(OC[C@@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O)=O
InChI key
MZZDOXWHMLEPLR-FZMBPTIQSA-N
관련 카테고리
일반 설명
The pacFA lipid attached to 2-oleoyl-sn-glycero-3-phosphocholine, contains a photoactivable diazirine ring with a clickable alkyne group.
생화학적/생리학적 작용
1-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-2-oleoyl-sn-glycero-3-phosphocholine (pacFA-18:1 PC) may be used for global analysis of protein–lipid interactions in living cells. pacFA acts as a precursor for the biosynthesis of bifunctional lipids. Proteins in contact with the bifunctional lipids are then cross-linked by ultraviolet (UV) irradiation of the diazirine ring. Finally, click chemistry is used to label the alkyne with a reporter molecule.
포장
2 mL Amber Serum Vial with Stopper and Crimp Cap (900408P-1mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Flash Point (°F)
No data available
Flash Point (°C)
No data available
Mathias J Gerl et al.
PloS one, 11(4), e0153009-e0153009 (2016-04-23)
Cell membranes contain hundreds to thousands of individual lipid species that are of structural importance but also specifically interact with proteins. Due to their highly controlled synthesis and role in signaling events sphingolipids are an intensely studied class of lipids.
In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.
Per Haberkant et al.
Angewandte Chemie (International ed. in English), 52(14), 4033-4038 (2013-03-02)
Per Haberkant et al.
Biochimica et biophysica acta, 1841(8), 1022-1030 (2014-01-21)
Understanding biological processes at the mechanistic level requires a systematic charting of the physical and functional links between all cellular components. While protein-protein and protein-nucleic acid networks have been subject to many global surveys, other critical cellular components such as
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