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890898C

Avanti

DOTMA

Avanti Research™ - A Croda Brand

동의어(들):

1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt)

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C42H84ClNO2
CAS 번호:
104872-42-6
Molecular Weight:
670.57
MDL number:
MFCD00145456
UNSPSC Code:
12352211
NACRES:
NA.25
기술 서비스
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도움 문의

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890898C-25mg), pkg of 2 × 4 mL (890898C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (890898C-25mg), 25 mg/mL (890898C-200mg)

application(s)

advanced drug delivery

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC.[Cl-]

InChI

1S/C42H84NO2.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,42H,6-19,24-41H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;

InChI key

LDGWQMRUWMSZIU-LQDDAWAPSA-M

Application

DOTMA is suitable for use in the synthesis of cationic microbubble.

Biochem/physiol Actions

DOTMA is a cationic lipid used as a non-viral vector for gene therapy. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome - cell membrane interaction.

Packaging

5 mL Clear Glass Sealed Ampule (890898C-200mg)
5 mL Clear Glass Sealed Ampule (890898C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

저장 등급

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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시험 성적서(COA)

Lot/Batch Number

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The use of cationic microbubbles to improve ultrasound-targeted gene delivery to the ischemic myocardium
Sun L, et al.
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Molecular therapy. Nucleic acids, 2, e84-e84 (2013-04-18)
MicroRNA-29b (miR-29b) expression has been shown to be reduced in non-small-cell lung cancer (NSCLC) tissues. Here, we have identified the oncogene cyclin-dependent protein kinase 6 (CDK6) as a direct target of miR-29b in lung cancer. We hypothesized that in vivo
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국제 무역 품목 번호

SKUGTIN
890898C-200MG04061837669026
890898C-25MG04061837669033