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Merck

850164P

Avanti

18:0-20:4 PI(3,5)P2

Avanti Research™ - A Croda Brand

동의어(들):

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-[phosphoinositol-3,5-bisphosphate] (ammonium salt); PIP2[3′,5′](18:0/20:4(5Z,8Z,11Z,14Z))

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C47H94N3O19P3
CAS 번호:
799268-58-9
Molecular Weight:
1098.18
MDL number:
MFCD22416814
UNSPSC 코드:
51191904
NACRES:
NA.25

주요 문서

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제품 이름

18:0-20:4 PI(3,5)P2, 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt), powder

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 100 μg (with stopper and crimp cap (850164P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850164P-500ug))

제조업체/상표

Avanti Research™ - A Croda Brand 850164P

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]

일반 설명

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

애플리케이션

18:0-20:4 PI(3,5)P2 or 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt) has been used:
  • in liposome preparation
  • in liposomes to check the lipid binding specificity of cortical sorting signal of integral membrane protein, Ist2 (CSSIst2) towards different phosphatidlyinositolphosphates (PIPs)
  • in giant unilamellar vesicles (GUVs) to study the interaction of cholesterol with phosphoinositides

포장

2 mL Amber Serum Vial with Stopper and Crimp Cap (850164P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850164P-500ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Marcel André Fischer et al.
Traffic (Copenhagen, Denmark), 10(8), 1084-1097 (2009-05-21)
Recruitment of cytosolic proteins to individual membranes is governed by a combination of protein-protein and protein-membrane interactions. Many proteins recognize phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] at the cytosolic surface of the plasma membrane (PM). Here, we show that a protein-lipid interaction can
Bong-Kwan Han et al.
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
Gerald R V Hammond et al.
Science (New York, N.Y.), 337(6095), 727-730 (2012-06-23)
The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfills many cellular functions in the plasma membrane (PM), whereas its synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used a combination of pharmacological and chemical

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