제품 이름
18:1 PI(3,4,5)P3, 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (with stopper and crimp cap (850156P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850156P-500ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850156P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
InChI key
CTYBALUTLRWYAN-CJXCTDJBSA-N
General description
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol is a structural phospholipid. Phosphatidylinositol phosphate (PIP) is located in the plasma membrane.
Application
18:1 PI(3,4,5)P3 is suitable to use in lipid stock preparation to form mixed micelles. It has also been used:
- in the preparation of planar-supported lipid bilayers (SLBs)
- in supplementing or enriching phagocyte membrane
- in liposome preparation
Biochem/physiol Actions
Phosphoinositol-containing sphingolipids can induce ATPase at lower levels when compared to glycerophospholipids.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850156P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850156P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Protein kinase Czeta exhibits constitutive phosphorylation and phosphatidylinositol-3, 4, 5-triphosphate-independent regulation
Tobias IS, et al.
The Biochemical Journal, 473(4), 509-523 (2016)
Phosphatidylinositol Turnover and Receptors
Ramazzotti G, et al.
Archives of Biochemistry and Biophysics (2016)
Achieving a graded immune response: BTK adopts a range of active/inactive conformations dictated by multiple interdomain contacts
Joseph RE, et al.
Structure, 25(10), 1481-1494 (2017)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 850156P-500UG | 04061835229666 |
| 850156P-100UG | 04061835229659 |