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Merck

840875C

Avanti

18:1 PA

Avanti Research - A Croda Brand

동의어(들):

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); DOPA; PA(18:1(9Z)/18:1(9Z))

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C39H72O8PNa
CAS 번호:
Molecular Weight:
722.95
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
기술 서비스
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description

1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt), chloroform solution

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840875C-25mg), pkg of 2 × 20 mL (840875C-1g), pkg of 2 × 4 mL (840875C-200mg), pkg of 5 × 4 mL (840875C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (840875C-25mg), 25 mg/mL (840875C-1g), 25 mg/mL (840875C-200mg), 25 mg/mL (840875C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na].[P](=O)(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC)(O)O

InChI

1S/C39H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44);/b19-17-,20-18-;/t37-;/m1./s1

InChI key

KHDHADSEKGCPKW-ZBFGHDQJSA-N

General description

18:1 PA (1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)) is a sodium salt of modified lipid which has phosphatidic acid group as the backbone.

Application

18:1 PA (1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)) has been used:
  • as a synthetic standard to identify the position of PA after iodine staining in phosphatidic acid assay by thin-layer chromatography (TLC)
  • as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions
  • as a lipid standard in radiolabeling analysis of phospholipids

Biochem/physiol Actions

Phosphatidic acid (PA) serves as a lipid messenger. It plays a key role in mammalian target of rapamycin (mTOR) signaling.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840875C-1g)
5 mL Clear Glass Sealed Ampule (840875C-200mg)
5 mL Clear Glass Sealed Ampule (840875C-25mg)
5 mL Clear Glass Sealed Ampule (840875C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

저장 등급

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문



Shutao Guo et al.
Journal of controlled release : official journal of the Controlled Release Society, 174, 137-142 (2013-11-28)
The poor solubility of cisplatin (CDDP) often presents a major obstacle in the formulation of CDDP in nanoparticles (NPs) by traditional methods. We have developed a novel method for synthesizing CDDP NPs taking advantage of its poor solubility. By mixing
Zhenping Cao et al.
Nature communications, 10(1), 5783-5783 (2019-12-21)
The gut microbiota represents a huge community of microorganisms that play essential roles in immune modulation and homeostasis maintenance. Microbiota transplantation is an important approach to prevent and treat disease as it can inhibit pathogen colonization and positively modulate bacterial
Shireesha Sankella et al.
The Journal of biological chemistry, 289(8), 4762-4777 (2014-01-16)
In this study we examined the role of phosphatidic acid (PA) in hepatic glucose production (HGP) and development of hepatic insulin resistance in mice that lack 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2). Liver lysophosphatidic acid and PA levels were increased ∼2- and



국제 무역 품목 번호

SKUGTIN
840875C-500MG04061837791741
840875C-1G04061837791710
840875C-200MG04061837791727
840875C-25MG04061837791734