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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C36H51BF2N2O
CAS 번호:
Molecular Weight:
576.61
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
description
23-(dipyrrometheneboron difluoride)-24-norcholesterol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810255P-1mg), pkg of 1 × 10 mg (810255P-10mg), pkg of 1 × 5 mg (810255P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Biomolecules attached to BODIPY, is readily absorbed in the visible light. It results in greater fluorescence quantum yields. It is highly photostable and less sensitive to change in polarity and pH.
Application
TOPFLUOR™Cholesterol is suitable:
- for cholesterol-uptake assay
- for BODIPY cholesterol labeling in live cell experiments
- for the formation of giant Janus liposomes via poly(vinyl alcohol) (PVA)-assisted lipid swelling
Biochem/physiol Actions
BODIPY labelled cholesterol has similar properties to that of the naïve cholesterol. This serves as a cholesterol marker for live cells and aids in trafficking intracellular cholesterol. It might also help in indicating lipid storage diseases.
Packaging
5 mL Amber Glass Screw Cap Vial (810255P-10mg)
5 mL Amber Glass Screw Cap Vial (810255P-1mg)
5 mL Amber Glass Screw Cap Vial (810255P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
wgk
WGK 3
문서
Explore full-spectrum fluorophores, fluorescent lipids, and probes for imaging, membrane studies, and labeling with TopFluor™, squaraines, and more.
Frederik W Lund et al.
BMC biophysics, 5, 20-20 (2012-10-20)
Cholesterol is an important membrane component, but our knowledge about its transport in cells is sparse. Previous imaging studies using dehydroergosterol (DHE), an intrinsically fluorescent sterol from yeast, have established that vesicular and non-vesicular transport modes contribute to sterol trafficking
Maarit Hölttä-Vuori et al.
Traffic (Copenhagen, Denmark), 9(11), 1839-1849 (2008-07-24)
Analysis of sterol distribution and transport in living cells has been hampered by the lack of bright, photostable fluorescent sterol derivatives that closely resemble cholesterol. In this study, we employed atomistic simulations and experiments to characterize a cholesterol compound with
Florly S Ariola et al.
Biophysical journal, 96(7), 2696-2708 (2009-04-08)
Cholesterol-rich, liquid-ordered (L(o)) domains are believed to be biologically relevant, and yet detailed knowledge about them, especially in live cells under physiological conditions, is elusive. Although these domains have been observed in model membranes, understanding cholesterol-lipid interactions at the molecular
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 810255P-1MG | 04061835185634 |
| 810255P-10MG | 04061835185627 |
| 810255P-5MG | 04061835185641 |