700184M
Avanti
desmosterol (D6) ester
Avanti Research™ - A Croda Brand
동의어(들):
111014
로그인조직 및 계약 가격 보기
크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C45H70D6O2
CAS 번호:
Molecular Weight:
655.12
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.12
제품 이름
desmosterol (D6) ester, 26,26,26,27,27,27-hexadeuteriocholesta-5,24-dien-3β-ol (9Z-octadecenoate), methylene chloride solution
분석
>99% (TLC)
양식
methylene chloride solution
포장
pkg of 1 × 1 mL (700184M-1mg)
제조업체/상표
Avanti Research™ - A Croda Brand 700184M
농도
1 mg/mL (700184M-1mg)
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Desmosterol is a precursor of cholesterol synthesis and the enzyme 24-dehydrocholesterol reductase catalyzes this step. It lacks a double bond between C24 and C25, which is present in cholesterol. Desmosterol is the major brain sterol and is localized in spermatozoa membrane and astrocytes. Desmosterol (D6) ester is a deuterated desmosterol with octadecanoic acid.
생화학적/생리학적 작용
Desmosterol is a liver X receptor (LXR) agonist and it regulates inflammatory signaling in macrophages. Desmosterol accumulates during impairment of 24-dehydrocholesterol reductase enzyme thereby leading to desmosterolosis. It is a potential therapeutic target for treating the neurodegenerative disorder.
포장
5 mL Clear Glass Sealed Ampule (700184M-1mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Central nervous system
WGK
WGK 2
Saara Vainio et al.
The Journal of biological chemistry, 281(1), 348-355 (2005-10-27)
Desmosterol is an immediate precursor of cholesterol in the Bloch pathway of sterol synthesis and an abundant membrane lipid in specific cell types. The significance of the difference between the two sterols, an additional double bond at position C24 in
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.