575659-U
HybridSPE®-PLus 96-Well solid phase extraction (SPE) Plate
Volume 2 mL, bed wt., 50 mg, pk of 1 ea
Synonym(s):
HybridSPE®-PLus
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About This Item
Product Name
HybridSPE®-PLus 96-Well Plate, volume 2 mL, pk of 1 ea
description
96-well Plate
Quality Level
product line
HybridSPE®
composition
bed wt., 50 mg
packaging
pk of 1 ea
technique(s)
solid phase extraction (SPE): suitable
volume
2 mL
matrix active group
zirconia-based phase
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General description
Our HybridSPE-PLus products offer the same time-proven chemistry of our traditional HybridSPE-Phospholipid products coupled with manufacturing enhancements that stem from years of production experience. These manufacturing enhancements have allowed us to increase flow consistency and reduce sample hold up volumes, further improving analyte recoveries and assay reproducibility. We invite customers to take advantage of the newest technology; HybridSPE-PLus.
Features and Benefits
- Simple 2-3 step standard methodology analogous to traditional protein precipitation provides simultaneous removal of both proteins and phospholipids
- Unique Lewis acid/base retention mechanism effectively removes phospholipids from both hydrophilic and hydrophobic analytes of interest (unlike competitive chemistries) eliminating phospholipid-induced ion suppression
- Highly reproducible, consistent product performance
- Provides cleaner samples for longer column life and less instrument downtime
- Available in 96-well and 1 mL cartridge dimensions
Legal Information
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Articles
This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.
Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components
Protocols
LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18
Immunoassay-based methods for digitoxin or digoxin exist, but are time consuming, labor intensive, and not selective due to similarities in their chemical structures.
Related Content
저분자는 일반적으로 분자량이 900달톤 미만인 이온 및 화합물입니다. 이러한 화합물은 주로 실리카 입자 또는 다양한 컬럼 화학(변형)을 가진 모놀리식 고정상을 사용하여 HPLC, UHPLC 및 LC-MS로 효과적으로 분리 및 분석할 수 있습니다.
고상 추출은 크로마토그래피 분석을 위해 시료를 정제하여 데이터 품질을 개선하고 분석 컬럼을 보호합니다.
Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).
Solid phase extraction purifies samples for chromatographic analysis, improving data quality and protecting analytical columns.
Chromatograms
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