SAB5600022
Anti-Histone H3 (unmodified Lys4) antibody, Rabbit monoclonal
recombinant, expressed in HEK 293 cells, clone RM186, purified immunoglobulin
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
recombinant
expressed in HEK 293 cells
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM186, monoclonal
recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 0.5- 1 μg/mL
immunocytochemistry: 0.5-2 μg/mL
western blot: 1-2 μg/mL
isotype
IgG
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... H3C1(8350)
Immunogen
Synthetic peptide corresponding to the N-terminus of Histone H3.
Biochem/physiol Actions
This antibody recognizes Histone H3 that is unmodified at Lys4 and does not recognize acetylated or methylated Lys4. The antibody binding specificity allows for modifications of Arg2, Thr3, and/or other modifications in Histone H3.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Antonella Muscella et al.
Journal of neurochemistry, 153(4), 525-538 (2019-11-16)
Following peripheral nerve injury, remnant Schwann cells adopt a migratory phenotype and remodel the extracellular matrix allowing axonal regrowth. Although much evidence has demonstrated that TGF-β1 promotes glioma cell motility and induces the expression of extracellular matrix proteins, the effects
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