SAB4504122
Anti-phospho-CaMK4 (pThr196/200) antibody produced in rabbit
affinity isolated antibody
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 51 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pThr196/pThr200)
Gene Information
human ... CAMK4(814)
General description
Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase. It is present in cells of the nervous and immune systems. This gene is located on human chromosome 5q22.
Immunogen
The antiserum was produced against synthesized peptide derived from human CaMK4 around the phosphorylation site of Thr196/200.
Immunogen Range: 166-215
Immunogen Range: 166-215
Biochem/physiol Actions
Calcium/calmodulin-dependent kinase 4 (CAMK4) controls blood pressure.This protein plays a major role in the spermatogenesis by phosphorylating protamines.. It controls vascular tone. Absence of CaMK4 gene promotes hypertension.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller
Racioppi L and Means AR
Trends in Immunology, 29(12), 600-607 (2008)
CaMK4 Gene Deletion Induces Hypertension
Santulli G
Journal of the American Heart Association (2012)
CAMK4 gene variation is associated with hypertension in a Uygur population
Chen SZ, et al.
Genetics and molecular research : GMR, 15(1) (2016)
A Khattri et al.
International journal of andrology, 35(6), 810-818 (2012-08-18)
Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase, which plays an important role in the spermatogenesis by phosphorylating protamines. It has been shown to be involved in the regulation of human sperm motility. Moreover, the Camk4 knockout
Genetic risk factors for the development of allergic disease identified by genome-wide association
Portelli MA, et al.
Clinical and Experimental Allergy, 45(1), 21-31 (2015)
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