R8900
Ro 8-4304
solid
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About This Item
Empirical Formula (Hill Notation):
C21H23FN2O3 · HCl
Molecular Weight:
406.88
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
solid
Quality level:
form
solid
Quality Level
solubility
H2O: ≤0.5 mg/mL
originator
Roche
storage temp.
2-8°C
SMILES string
Cl.NC(=O)c1ccc(OCCC(O)N2CCC(=CC2)c3ccc(F)cc3)cc1
InChI
1S/C21H23FN2O3.ClH/c22-18-5-1-15(2-6-18)16-9-12-24(13-10-16)20(25)11-14-27-19-7-3-17(4-8-19)21(23)26;/h1-9,20,25H,10-14H2,(H2,23,26);1H
InChI key
NYFXHCMXYODFLP-UHFFFAOYSA-N
Gene Information
human ... GRIN2B(2904)
Biochem/physiol Actions
NR2B-selective, noncompetitive NMDA glutamate receptor antagonist
Features and Benefits
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Related Content
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| R8900-25MG | 04061832273860 |
| R8900-5MG | 04061832084466 |