I0250

Imidazole

Name: Imidazole
Brand: SIGMA

≥99% (titration), crystalline

Synonym(s):

1,3-Diaza-2,4-cyclopentadiene, Glyoxaline

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About This Item

Empirical Formula (Hill Notation):

C₃H₄N₂

CAS Number:

288-32-4

Molecular Weight:

68.08

Beilstein:

103853

EC Number:

206-019-2

MDL number:

MFCD00005183

UNSPSC Code:

12352005

eCl@ss:

39161001

PubChem Substance ID:

24895898

NACRES:

NA.25

Key Documents

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vapor pressure

<1 mmHg ( 20 °C)

Quality Level

300

Assay

≥99% (titration)

form

crystalline

impurities

≤0.005% Fluorescence blank (β-NADH equivalence.)

color

white

pH

6.2-7.8 (25 °C)

pKa (25 °C)

6.95

bp

256 °C (lit.)

mp

88-91 °C (lit.)

solubility

water: 500 mg/mL, clear, colorless to very faintly yellow

storage temp.

room temp

SMILES string

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChI key

RAXXELZNTBOGNW-UHFFFAOYSA-N

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Biochemicals

Biological Buffers

Application

Excellent for buffers in the range of pH 6.2-7.8

Pictograms

GHS08,GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H314,H360D

Precautionary Statements

P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

293.0 °F - closed cup

Flash Point(C)

145 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors.

Peter Canning et al.

Journal of molecular biology, 426(13), 2457-2470 (2014-04-29)

The discoidin domain receptors (DDRs), DDR1 and DDR2, form a unique subfamily of receptor tyrosine kinases that are activated by the binding of triple-helical collagen. Excessive signaling by DDR1 and DDR2 has been linked to the progression of various human

Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy.

Pam M Van Ry et al.

Molecular therapy : the journal of the American Society of Gene Therapy, 23(8), 1285-1297 (2015-06-09)

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by mutations in the dystrophin gene, leading to the loss of a critical component of the sarcolemmal dystrophin glycoprotein complex. Galectin-1 is a small 14 kDa protein normally found in skeletal

Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis.

Ali Tebbi et al.

The Journal of biological chemistry, 290(22), 14077-14090 (2015-04-17)

Ribonucleotide reductase (RnR) is a key enzyme synthesizing deoxyribonucleotides for DNA replication and repair. In mammals, the R1 catalytic subunit forms an active complex with either one of the two small subunits R2 and p53R2. Expression of R2 is S

Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52.

William A Gaines et al.

Nature communications, 6, 7834-7834 (2015-07-29)

The conserved budding yeast Rad51 paralogues, including Rad55, Rad57, Csm2 and Psy3 are indispensable for homologous recombination (HR)-mediated chromosome damage repair. Rad55 and Rad57 are associated in a heterodimer, while Csm2 and Psy3 form the Shu complex with Shu1 and

Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex.

Michael D Clark et al.

Proceedings of the National Academy of Sciences of the United States of America, 112(28), E3669-E3678 (2015-07-01)

Acetylation is correlated with chromatin decondensation and transcriptional activation, but its regulation by histone deacetylase (HDAC)-bearing corepressor complexes is poorly understood. Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed

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Protocols

Sildenafil Citrate USP Method Using HPTLC Plates for the Limit of Imidazole Test

In the present study we demonstrate compliance of silica gel 60 F254 HPTLC plates with USP requirements, and how HPTLC plates are suitable for the Sildenafil citrate-Limit of Imidazole test.

Imidazole

≥99% (titration), crystalline

Select a Size

About This Item

Key Documents

Properties

vapor pressure

Quality Level

Assay

form

impurities

color

pH

pKa (25 °C)

bp

mp

solubility

storage temp.

SMILES string

InChI

InChI key

Related Categories

Description

Application

Safety Information

Pictograms

Signal Word

Hazard Statements

Precautionary Statements

Hazard Classifications

Storage Class Code

WGK

Flash Point(F)

Flash Point(C)

Personal Protective Equipment

Documentation

Certificates of Analysis (COA)

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Peer Reviewed Papers

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Protocols

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