C8863
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine
≥98% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C23H22N4O
CAS Number:
Molecular Weight:
370.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: soluble 17 mg/mL at ≤60 °C
storage temp.
2-8°C
SMILES string
Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C5CCCC5
InChI
1S/C23H22N4O/c24-22-21-20(14-27(17-6-4-5-7-17)23(21)26-15-25-22)16-10-12-19(13-11-16)28-18-8-2-1-3-9-18/h1-3,8-15,17H,4-7H2,(H2,24,25,26)
InChI key
FMETVQKSDIOGPX-UHFFFAOYSA-N
Biochem/physiol Actions
A potent and selective pyrrolo[2,3-d]pyrimidine Lck inhibitor.
Potent and selective inhibitor of Lck, a src family tyrosine kinase.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| C8863-5MG | 04061832445328 |
| C8863-25MG | 04061832445311 |