A4159
L-Asparagine
BioReagent, suitable for cell culture, suitable for insect cell culture
Synonym(s):
(S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide
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About This Item
Linear Formula:
H2NCOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
132.12
Beilstein:
1723527
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.75
product line
BioReagent
Quality Level
Assay
≥98% (HPLC)
form
powder
technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
color
white
mp
235 °C (dec.) (lit.)
application(s)
agriculture
SMILES string
N[C@@H](CC(N)=O)C(O)=O
InChI
1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1
InChI key
DCXYFEDJOCDNAF-REOHCLBHSA-N
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Application
L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine.
An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.
An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Increased translation efficiency and antizyme-dependent stabilization of ornithine decarboxylase in amino acidsupplemented human colon adenocarcinoma cells, Caco-2.
Chabanon, H., et al.
The Biochemical Journal, 348 (Pt 2), 401-408 (2000)
Interaction of asparagine and EGF in the regulation of ornithine decarboxylase in IEC-6 cells
Ray, R. M., et al.
The American Journal of Physiology, 276 (3 Pt 1), G773-G780 null
The enantiospecific synthesis of an isoxazoline. A RGD mimic platelet GPIIb/IIIa antagonist.
Zhang L. H., et al.
The Journal of Organic Chemistry, 62, 2466-270 (1997)
Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis
Cabrera-Martinez, R. M., et al.
Journal of Bacteriology, 185, 2457-264 (2003)
Homochiral 4-azalysine building blocks: syntheses and applications in solid-phase chemistry
Chhabra, S. R., et al.
The Journal of Organic Chemistry, 67, 4017-4029 (2002)
Related Content
Chromatograms
application for HPLC
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