42874
Tetramethylrhodamine isothiocyanate–Dextran
average mol wt 40,000
Synonym(s):
TRITC-Dextran 40, TRITC-Dextran
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About This Item
biological source
synthetic
Quality Level
form
powder
mol wt
average mol wt 40,000
extent of labeling
0.001-0.008 mol/mol TRITC glucose
fluorescence
λex 550 nm; λem 577 nm±5 nm in 0.1 M Tris pH 8.0
application(s)
cell analysis
General description
Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 40, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.
Application
Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 40) is used as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular drug delivery.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Explore FITC-labelled polysaccharides and their properties, including impact of molecular weight on molecule dimensions.
J David Symons et al.
Arteriosclerosis, thrombosis, and vascular biology, 22(5), 772-780 (2002-05-15)
High circulating concentrations of homocysteine (ie, hyperhomocysteinemia [Hhcy]) impair the vascular function of peripheral conduit arteries and arterioles perfusing splanchnic and skeletal muscle regions. The effects of HHcy on coronary resistance vessel function and other indexes of vascular function, ie
Kimberley J Reeves et al.
Journal of vascular research, 49(2), 132-143 (2012-01-21)
This study evaluated four fluorescent-protein conjugates to monitor microcirculatory variables using the murine cremaster muscle and determined acute and long-term responses to repeated administration of FITC-BSA [conjugated at the University of Sheffield (UoS)] within a dorsal microcirculatory chamber (DMC) in
Andrea Kassner et al.
Neuroimaging clinics of North America, 21(2), 315-325 (2011-06-07)
The blood-brain barrier (BBB) is a functional concept to describe unique features of intracranial blood vessels that prevent many substances in the systemic circulation from entering the brain. In the setting of acute ischemic stroke, loss of blood-brain barrier (BBB)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D2135-100MG | 04061833561652 |
| D2135-1G | 04061833561669 |
| 800816C-25MG | 04061838169624 |
| 800816P-200MG | 04061835533909 |
| 800816P-10MG | 04061835533893 |
| 800816C-10MG | 04061838169617 |
| 800816P-25MG | 04061835533916 |
| 810156C-1MG | 04061837666490 |
| D2135-250MG | 04061832947198 |
| 42874-1G | 04061826643372 |