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Merck

30461

Sigma-Aldrich

DEAE-Dextran hydrochloride

BioReagent, Molecular Biology

Synonym(s):

Diethylaminoethyl-dextran hydrochloride

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About This Item

CAS Number:
9064-91-9
MDL number:
MFCD00081561
UNSPSC Code:
12352201
NACRES:
NA.25

Key Documents

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Molecular Biology

Quality Level

100

product line

BioReagent

form

solid

impurities

DNases, none detected
 RNases, none detected
 phosphatases, none detected
 proteases, none detected

solubility

H2O: 0.1 g/mL, clear

storage temp.

room temp

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Application

DEAE-Dextran, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF8182
BCBZ8251
BCCB3123
BCBN1143V
1396877

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S Tabor et al.
Current protocols in immunology, Chapter 10, Unit 10-Unit 10 (2008-04-25)
Extensive knowledge of the enzymology involved in biosynthesis and degradation of nucleic acids has permitted the development of simple methods for labeling RNA and DNA with radioisotopes or biotin. These labeled probes are used primarily for hybridization to nucleic acid
Transfection using DEAE-dextran.
Gulick T.
Current Protocols in Cell Biology, doi: 10-doi: 10 (2003)
J Zarate et al.
Journal of microencapsulation, 28(7), 614-620 (2011-07-12)
Bovine serum albumin (BSA) loaded calcium alginate microparticles (MPs) produced in this study by a w/o emulsification and external gelation method exhibited spherical and fairly smooth and porous morphology with 1.052 ± 0.057 µm modal particle size. The high permeability of the calcium
DEAE-dextran transfection of lymphocyte cell lines.
Smale ST.
Cold Spring Harbor Protocols, doi: 10-doi: 10 (2010)
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were
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Related Content

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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