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Merck

472301

Sigma-Aldrich

Dimethyl sulfoxide

ACS reagent, ≥99.9%

Synonym(s):

DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
67-68-5
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
200-664-3
MDL number:
MFCD00002089
UNSPSC Code:
12191502
PubChem Substance ID:
329757302
NACRES:
NA.21
Grade:
ACS reagent
Assay:
≥99.9%
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)

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grade

ACS reagent

Quality Level

200

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

dilution

(for analytical testing)

impurities

≤0.001 meq/g Titr. acid
≤0.1% water

evapn. residue

≤0.01%

color

clear colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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General description

Dimethyl sulfoxide is an organosulfur, commonly used as a polar solvent that can dissolve a wide range of polar and non-polar compounds. It is also utilized as a reaction reagent in several well-known processes, including swern oxidation, 2a pfitzner-moffatt oxidation, 2b, and the corey-chaykovsky reaction.
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

Application

Dimethyl sulfoxide (DMSO) has been used:
  • in the preparation of ethyl 4-[18F]fluorobenzoate.
  • in the culture medium for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay.
  • as a solvent in chemical synthesis.
  • to dissolve and prepare stock solutions of small molecules, drugs, and chemical compounds for various assays and experiments.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP1528
MKCP0761
MKCP0762
MKCP0759
MKCP0758

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Shuang Hou et al.
Journal of visualized experiments : JoVE, (52)(52), doi:10-doi:10 (2011-07-07)
Biomolecules, including peptides¹⁻⁹, proteins¹⁰⁻¹¹, and antibodies and their engineered fragments¹²⁻¹⁴, are gaining importance as both potential therapeutics and molecular imaging agents. Notably, when labeled with positron-emitting radioisotopes (e.g., Cu-64, Ga-68, or F-18), they can be used as probes for targeted
P Roy et al.
The FEBS journal, 277(2), 441-452 (2009-12-18)
EVI1 is a nuclear zinc finger protein essential to normal development, which participates in acute myeloid leukaemia progression and transforms Rat1 fibroblasts. In this study we show that enforced expression of Evi1 in Rat1 fibroblasts protects from paclitaxel-induced apoptosis, consistent
A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE.
S HAKOMORI
Journal of biochemistry, 55, 205-208 (1964-02-01)
Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.
Omura K and Swern D.
Tetrahedron, 34(11), 1651-1660 (1978)
Amino acid analysis: aqueous dimethyl sulfoxide as solvent for the ninhydrin reaction.
S Moore
The Journal of biological chemistry, 243(23), 6281-6283 (1968-12-10)
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Solvent Miscibility Table

Substances are said to be miscible in one another if they dissolve to form a uniform solution. Bookmark or download our miscibility table for common lab solvents.

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