64340
DL-Methionine
≥99.0% (NT)
Synonym(s):
(±)-2-Amino-4-(methylmercapto)butyric acid, DL-2-Amino-4-(methylthio)butanoic acid
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About This Item
Linear Formula:
CH3SCH2CH2CH(NH2)COOH
CAS Number:
Molecular Weight:
149.21
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-432-1
MDL number:
Beilstein/REAXYS Number:
636185
Product Name
DL-Methionine, ≥99.0% (NT)
Quality Level
assay
≥99.0% (NT)
form
powder or crystals
optical activity
[α]/D, c = 5 in 5 M HCl (inactive)
concentration
5% in 5 M HCl
ign. residue
≤0.05%
color
white
mp
280 °C (dec.) (lit.)
solubility
5 M HCl: 1 g/10 mL, clear, colorless to almost colorless
suitability
corresponds for TLC
application(s)
peptide synthesis
SMILES string
CSCCC(N)C(O)=O
InChI
1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChI key
FFEARJCKVFRZRR-UHFFFAOYSA-N
Application
DL-Methionine has been used to study the susceptibility of methionine to oxidation during the development of monoclonal antibodies.
Biochem/physiol Actions
Methionine is an essential amino acid which acts a precursor for transmethylation and transsulfuration. In proteins, L-methionine is the biologically active form. D-methionine is converted to L-methionine by enzymes in the body. The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine′s metabolic product glutathione is known to regulate immune response and has antiviral action.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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L-methionine as immune supportive supplement: a clinical evaluation.
Van Brummelen and du Toit D
Amino Acids, 33(1), 157-163 (2007)
Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies
Rong Yang
MAbs (2017)
Il Jin Cho et al.
Biochemical and biophysical research communications, 367(1), 190-194 (2008-01-02)
We investigated the hypolipidemic effect of resveratrol focused on the mRNA expression and hepatic HMG-CoA reductase (HMGR) activity in hamsters fed a high-fat diet. Male Syrian Golden hamsters were fed a high-fat diet containing 0.025% fenofibrate or 0.025% resveratrol for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 93659-250G | 04061833441428 |
| 1700501-200MG | 04061838750365 |
| 1083740100 | 04022536103549 |
| 1083740500 | 04022536103556 |
| 1083749010 | 04022536692838 |
| 1083961000 | 04022536104003 |
| T8941-100G | 04061837379871 |
| T2610000 | 04061837342592 |
| T0254-100G | 04061835363056 |
| T0254-1KG | 04061837334634 |
| T0254-25G | 04061835363063 |
| T0254-500G | 04061837334641 |
| 93659-10G | 04061833283059 |
| 51145-100MG | 04061832491271 |
| 51145-1G | 04061834232766 |
| 6540-100GM | 04055977184563 |
| 8160170025 | 04022536423852 |
| 8160170100 | 04022536423869 |