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Merck

ECM554

Sigma-Aldrich

QCM ECMatrix Cell Invasion Assay, 24-well (8 µm), fluorimetric

The Cell Invasion Assay Kit kuses a 24 well plate with 8 um pores, which is ideal for evaluation of invasive tumor cells.

Synonym(s):

Cell invasion assessment kit

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About This Item

UNSPSC Code:
12352207
eCl@ss:
32161000
NACRES:
NA.84

Key Documents

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Quality Level

100

species reactivity

vertebrates

manufacturer/tradename

Chemicon®
QCM

technique(s)

cell based assay: suitable

detection method

fluorometric

shipped in

wet ice

Related Categories

Application

Research Category
Cell Structure
The CHEMICON® Cell Invasion Assay Kit is ideal for evaluation of invasive tumor cells. Each CHEMICON Cell Invasion Assay Kit contains sufficient reagents for the evaluation of 24 samples. The quantitative nature of this assay is especially useful for screening of pharmacological agents.

The CHEMICON Cell Invasion Assay Kit is intended for research use only; not for diagnostic or therapeutic applications.
The Cell Invasion Assay Kit kuses a 24 well plate with 8 um pores, which is ideal for evaluation of invasive tumor cells.

Packaging

24 assays

Preparation Note

Store kit materials at 2-8°C for up to their expiration date. Do not freeze.

Other Notes

Sterile 24-well Cell Invasion Plate Assembly: (Part No. 70019) Two 24-well plates with 12 ECMatrixTM-coated inserts per plate (24 coated inserts total/kit for 24 assays).

Cell Detachment Solution: (Part Number 90131) One bottle - 16 mL.

4X Cell Lysis Buffer: (Part Number 90130) One bottle - 16 mL.

CyQuant GR Dye 1: (Part Number 90132) One vial - 75 mL

Forceps: (Part Number 10203) One each.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

CorrosionEnvironment
GHS05,GHS09

Signal Word

Danger

Hazard Statements

H318,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kate Lawrenson et al.
Carcinogenesis, 32(10), 1540-1549 (2011-08-24)
The biology underlying early-stage epithelial ovarian cancer (EOC) development is poorly understood. Identifying biomarkers associated with early-stage disease could have a significant impact on reducing mortality. Here, we describe establishment of a three-dimensional (3D) in vitro genetic model of EOC
Bei Wang et al.
Journal of hepatology, 50(3), 528-537 (2009-01-22)
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide with poor prognosis associated with tumor invasion and metastasis. The tumor suppressor p53 plays critical roles in tumor development, but there is increasing evidence for its involvement
Ping Feng et al.
The international journal of biochemistry & cell biology, 40(1), 98-109 (2007-08-19)
Cyr61/CCN1 is a secreted extracellular matrix associated protein involved in diverse biological functions and plays multiple roles in tumorigenesis. Cyr61 was down-regulated in HCC tumor tissues as observed in our previous cDNA microarray study, but its potential role in hepatocarcinogenesis
Xu-Jun He et al.
Cancer science, 103(12), 2082-2091 (2012-09-11)
Recent studies have shown that overexpression of regenerating gene family member 4 (REG4) is associated with the initiation and progression of pancreatic cancer. In our study, we explored the role of REG4 in the invasion of pancreatic cancer. Real-time PCR
Yukuan Feng et al.
European journal of cancer (Oxford, England : 1990), 47(15), 2353-2363 (2011-06-18)
Vascular endothelial growth factor C (VEGF-C) expression is associated with the malignant tumour phenotype making it an attractive therapeutic target. We investigated the biological roles of VEGF-C in tumour growth, migration, invasion and explored the possibility of VEGF-C as a
View All Related Papers

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Cell Migration and Invasion: Choosing the Right Assay

Cell migration is stimulated and directed by interaction of cells with the extracellular matrix (ECM), neighboring cells, or chemoattractants. Cell migration participates in morphogenic processes, wound healing and tumor metastasis. Specifically, inhibiting tumor invasion by blocking tumor cell chemotaxis has been a major focus of research. Tumor cell invasion, marked by degradation of ECM, is also directly correlated with metastatic potential.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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