Skip to Content
Merck

Key Documents

View All Documentation

536954

Rosmarinic acid

96%

Synonym(s):

(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C18H16O8
CAS Number:
20283-92-5
Molecular Weight:
360.31
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
24878185
MDL number:
MFCD00017740
Beilstein/REAXYS Number:
2227587
Assay:
96%
Form:
powder
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

200

assay

96%

form

powder

mp

171-175 °C (lit.)

functional group

carboxylic acid, ester

SMILES string

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2

InChI

1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1

InChI key

DOUMFZQKYFQNTF-WUTVXBCWSA-N

Gene Information

human ... LCK(3932)

General description

Rosmarinic acid is a bioactive plant phenolic compound with antioxidant and anti-inflammatory effects.

Application

Rosmarinic acid has been used as a model compound to study its biological effects in animal models. Various studies have shown its ability to:
  • Inhibit nephropathy.
  • Inhibit gentamicin sulfate (GS)-induced renal oxidative damage.
  • Reduce noise-induced hearing loss.
  • Reduce depression.
  • Reduce post-traumatic stress disorder (PTSD)-like symptoms.

Still not finding the right product?

Explore all of our products under Rosmarinic acid

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBB0241
03202HJ
07902PH
U22521
07128TE

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Daseul Kim et al.
Pharmaceutics, 11(7) (2019-06-30)
Amongst various drug administration methods, ophthalmic drug delivery has been a useful way for the treatment of eye-related diseases. However, therapeutic efficacy of ocular therapy for anterior or posterior eye segments through topical administration is considerably challenged by the number
Rosmarinic acid ameliorates PTSD-like symptoms in a rat model and promotes cell proliferation in the hippocampus.
Nie H, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 51, 16-22 (2014)
Rosmarinic acid up-regulates the noise-activated Nrf2/HO-1 pathway and protects against noise-induced injury in rat cochlea.
Fetoni A R, et al.
Free Radical Biology & Medicine, 83, 269-281 (2015)
View All Related Papers

Global Trade Item Number

SKUGTIN
536954-5G04061835289073