SRP5144
Stathmin, His tagged human
recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
C1orf215, FLJ32206, LAP18, Lag, MGC138869, MGC138870, OP18, PP17, PP19, PR22, SMN, STMN1
biological source
human
recombinant
expressed in E. coli
Assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~19 kDa
NCBI accession no.
application(s)
cell analysis
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... STMN1(3925)
Physical form
Supplied in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
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STMN1 overexpression correlates with biological behavior in human cutaneous squamous cell carcinoma.
Li X
Pathology Research and Practice, 211(11), 816-823 (2015)
Covalent modification of stathmin by CCNU determined by FTMS analysis of modified proteins and tryptic peptides.
Wu WW
Biochemical and Biophysical Research Communications, 367(1), 7-13 (2008)
The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network.
Gavet O
Journal of Cell Science, 111(Pt 22), 3333-3346 (1998)
O Gavet et al.
Journal of cell science, 111 ( Pt 22), 3333-3346 (1998-10-28)
Stathmin is a small regulatory phosphoprotein integrating diverse intracellular signaling pathways. It is also the generic element of a protein family including the neural proteins SCG10, SCLIP, RB3 and its two splice variants RB3' and RB3". Stathmin itself was shown
A Sobel
Trends in biochemical sciences, 16(8), 301-305 (1991-08-01)
Stathmin is a ubiquitous, phylogenetically conserved protein present in the cytoplasm of cells in a variety of unphosphorylated and phosphorylated forms. Its expression and phosphorylation are regulated throughout development and in response to extracellular signals regulating cell proliferation, differentiation and
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