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Merck

6.18729

Trifluoroacetic acid

suitable for chromatography

Synonym(s):

Trifluoroacetic acid solution, TFA

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About This Item

Linear Formula:
CF3COOH
CAS Number:
Molecular Weight:
114.02
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
5446934
MDL number:
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Quality Level

suitability

suitable for chromatography

SMILES string

OC(=O)C(F)(F)F

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

General description

Trifluoroaceticacid (TFA) is used as an additive in HPLC and LC-MS analyses to improve theseparation of basic compounds.

Application

Trifluoroacetic acid can be used as:
  • Ion-pairing reagent in reversed-phase liquid chromatography (RPLC) for peptide separation.
  • An acidic additive in the mobile phase for chiral supercritical fluid chromatography.


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pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2



Certificates of Analysis (COA)

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