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Merck

6.18665

Acetic acid glacial

suitable for chromatography

Synonym(s):

Acetic acid, Glacial acetic acid

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About This Item

Linear Formula:
CH3CO2H
CAS Number:
Molecular Weight:
60.05
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
506007
MDL number:
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vapor density

2.07 (vs air)

Quality Level

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F, 4 %, 59 °F

refractive index

n20/D 1.371 (lit.)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.04 g/mL at 25 °C (lit.)

suitability

suitable for chromatography

SMILES string

[F2C(F2C)13F3C]C(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

General description

Glacial acetic acid is commonly used as an eluent additive in high-performance liquid chromatography (HPLC) and thin-layer chromatography (TLC).

Application

Acetic acid glacial can be used as:
  • Elution solvent in the high-performance liquid chromatography (HPLC) method for the quantification of trans, trans-muconicacid in human urine.
  • Mobile phase component in an isocratic HPLC (high-performance liquid chromatography) procedure to facilitate the separation and analysis of Glycyrrhiz in and its aglycone, 18β-glycyrrhetic acid.


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Certificates of Analysis (COA)

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