181104C
Avanti
Liver Extract Total
Avanti Research™ - A Croda Brand
Synonym(s):
Liver Total Lipid Extract (Bovine)
form
chloroform solution
packaging
pkg of 1 × 4 mL (181104C-100mg)
pkg of 5 × 4 mL (181104C-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
25 mg/mL (181104C-100mg)
25 mg/mL (181104C-500mg)
lipid type
lipid extracts
shipped in
dry ice
storage temp.
−20°C
General description
Total Lipid Extract is a chloroform:methanol extract of the respective tissue (Brain, Soybean, Heart, etc.). This extract is partitioned against deionized water, and the chloroform phase is concentrated.
Application
Liver extract total has been used for the identification of cholesterol as an endogenous ligand of human macrophage-inducible C-type lectin (hMincle).
Packaging
5 mL Clear Glass Sealed Ampule (181104C-100mg)
5 mL Clear Glass Sealed Ampule (181104C-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
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Human Mincle binds to cholesterol crystals and triggers innate immune responses
Kiyotake R, et al.
The Journal of biological chemistry, 290(42), 25322-25332 (2015)
Filip Duša et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183115-183115 (2019-11-11)
The cell membrane is mainly composed of lipid bilayers with inserted proteins and carbohydrates. Lipid bilayers made of purified or synthetic lipids are widely used for estimating the effect of target compounds on cell membranes. However, the composition of such
Ryoko Kiyotake et al.
The Journal of biological chemistry, 290(42), 25322-25332 (2015-08-25)
C-type lectin receptors (CLRs) are an emerging family of pattern recognition receptors that recognizes pathogens or damaged tissue to trigger innate immune responses. However, endogenous ligands for CLRs are not fully understood. In this study, we sought to identify an
Giuseppe Paglia et al.
Nature protocols, 12(4), 797-813 (2017-03-17)
Metabolomics and lipidomics aim to profile the wide range of metabolites and lipids that are present in biological samples. Recently, ion mobility spectrometry (IMS) has been used to support metabolomics and lipidomics applications to facilitate the separation and the identification
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