Key Documents

View All Documentation

A0887

5α-Androstane

Name: 5α-Androstane
Brand: SIGMA

Synonym(s):

Etioallocholane

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₉H₃₂

CAS Number:

438-22-2

Molecular Weight:

260.46

NACRES:

NA.77

PubChem Substance ID:

24890466

UNSPSC Code:

12352211

EC Number:

207-116-2

MDL number:

MFCD00067600

Form:

powder

Assay:

≥99% (HPLC)

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

assay

≥99% (HPLC)

Quality Level

200

form

powder

solubility

chloroform: 49-51 mg/mL, clear, colorless

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CC[C@@]3([H])CCCC[C@]3(C)[C@@]1([H])CC[C@]4(C)CCC[C@@]24[H]

InChI

1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14-,15+,16+,17+,18+,19+/m1/s1

InChI key

QZLYKIGBANMMBK-UGCZWRCOSA-N

Gene Information

human ... UGT1A4(54657)

Description

Application

5α-Androstane has been used to treat androgen-dependent and androgen-independent prostate cancer cells (LNCaP and PC-3) to investigate cell proliferation, viability, adhesion and hormone expression.

Other Notes

Serves as the parent steroid skeleton for all androgens, but the hydrocarbon itself is not naturally occurring.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Estrogen and androgen hormone levels modulate the expression of PIWI interacting RNA in prostate and breast cancer

Oner C, et al.

PLoS ONE, 11(7), e0159044-e0159044 (2016)

Degradation of petroleum hydrocarbons in seawater by simulated surface-level atmospheric ozone: Reaction kinetics and effect of oil dispersant.

Haodong Ji et al.

Marine pollution bulletin, 135, 427-440 (2018-10-12)

Oil degradation by surface-level atmospheric ozone has been largely ignored in the field. To address this knowledge gap, this study investigated the ozonation rate and extent of typical petroleum compounds by simulated surface-level ozone, including total petroleum hydrocarbons (TPHs), n-alkanes

Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor.

Kaoru Kobayashi et al.

Drug metabolism and disposition: the biological fate of chemicals, 33(7), 924-929 (2005-04-02)

Constitutive active (or androstane) receptor (CAR, NR1I3), a member of the nuclear receptor family, is a major regulator for induction of cytochrome P450 2B (CYP2B) genes by phenobarbital. Phenobarbital-like inducer, 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is a potent mouse CAR ligand that has been

View All Related Papers

Global Trade Item Number

SKU	GTIN
A0887-100MG	04061833334577
A0887-1G	04061826752111