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810332C

Avanti

18:1 PE CF

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C62H94N3O14P
CAS Number:
799268-49-8
Molecular Weight:
1136.40
MDL number:
MFCD22416785
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

18:1 PE CF, Avanti Research™ - A Croda Brand

assay

>99% (TLC)

form

solution

packaging

pkg of 1 × 1 mL (810332C-1mg), pkg of 5 × 1 mL (810332C-5mg), pkg of 5 × 2 mL (810332C-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL (810332C-10mg), 1 mg/mL (810332C-1mg), 1 mg/mL (810332C-5mg)

lipid type

fluorescent lipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 PE CF is a green fluorescent tagged phosphatidylethanolamine.

Application

18:1 PE CF may be used:
  • to spike human serum
  • to prepare concentrated lipid mix, PC:PE:fluoPE to assess basal binding properties and PC:PE:fluoPE:PIP to assess specific binding properties of the protein to each phosphoinositides (PIP)
  • to prepare the large unilamellar vesicles (LUVs)
  • in the preparation of fluorescent phosphoinositide?containing liposomes
  • for fluorescent labeling of total lipids to the initial liposome formulation mixture
  • in the formulation of pegylated magneto-liposomes (MLs) and transferrin (Tf) embedding

Biochem/physiol Actions

Phosphatidylethanolamine controls the membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).

Packaging

5 mL Amber Glass Screw Cap Vial (810332C-10mg)
5 mL Amber Glass Screw Cap Vial (810332C-1mg)
5 mL Amber Glass Screw Cap Vial (810332C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

67-66-3

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Protein-Lipid Interaction by Fluorescence (PLIF) to Characterize and Screen for Inhibitors of Protein-Phosphoinositide Interactions
Ceccato L, et al.
Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.], 89(1), 19-31 (2017)
Liposome Flotation Assays for Phosphoinositide-protein Interaction
Tronchere H and Boal F
Journal of Cell Science, 390(1), 1-13 (2015)
NUTS and BOLTS: applications of fluorescence-detected sedimentation
Kroe RR and Laue TM
Analytical biochemistry, 390(1), 1-13 (2009)
View All Related Papers

Global Trade Item Number

SKUGTIN
810332C-5MG04061837667275
810332C-10MG04061837667251
810332C-1MG04061837667268