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A72405

2-Amino-1-phenylethanol

Name: 2-Amino-1-phenylethanol
Brand: ALDRICH

98%

Synonym(s):

α-(Aminomethyl)benzyl alcohol, DL-β-Hydroxyphenethylamine, Phenylethanolamine

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About This Item

Linear Formula:

NH₂CH₂CH(OH)C₆H₅

CAS Number:

7568-93-6

Molecular Weight:

137.18

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891194

EC Number:

231-469-1

Beilstein/REAXYS Number:

971222

MDL number:

MFCD00008137

Assay:

98%

Form:

solid

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Properties

Quality Level

100

assay

98%

form

solid

bp

160 °C/17 mmHg (lit.)

mp

56-58 °C (lit.)

SMILES string

NCC(O)c1ccccc1

InChI

1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2

InChI key

ULSIYEODSMZIPX-UHFFFAOYSA-N

Gene Information

human ... PNMT(5409)

Description

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.

Erkan Karakas et al.

Nature, 475(7355), 249-253 (2011-06-17)

Since it was discovered that the anti-hypertensive agent ifenprodil has neuroprotective activity through its effects on NMDA (N-methyl-D-aspartate) receptors, a determined effort has been made to understand the mechanism of action and to develop improved therapeutic compounds on the basis

Expression of neuropeptide hormone receptors in human adrenal tumors and cell lines: antiproliferative effects of peptide analogues.

C G Ziegler et al.

Proceedings of the National Academy of Sciences of the United States of America, 106(37), 15879-15884 (2009-09-01)

Peptide analogues targeting various neuropeptide receptors have been used effectively in cancer therapy. A hallmark of adrenocortical tumor formation is the aberrant expression of peptide receptors relating to uncontrolled cell proliferation and hormone overproduction. Our microarray results have also demonstrated

Phenylethanolaminotetralines compete with [3H]dihydroalprenolol binding to rat colon membranes without evidencing atypical beta-adrenergic sites.

M Landi et al.

Biochemical pharmacology, 44(4), 665-672 (1992-08-18)

[3H]Dihydroalprenolol ([3H]DHA) specific binding (determined by the difference in the presence and absence of 20 microM (-)isoprenaline) to rat colon membranes was saturable (Bmax = 39.6 fmol/mg protein), of high affinity (Kd = 0.87 nM) and stereospecific (IC50 330 and

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Global Trade Item Number

SKU	GTIN
A72405-10G	04061833383896
A72405-50G	04061832281469