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About This Item
Empirical Formula (Hill Notation):
C21H18N2O2
CAS Number:
Molecular Weight:
330.38
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Quality Level
assay
98%
optical activity
[α]22/D +353°, c = 3.7 in chloroform
mp
204-206 °C (lit.)
functional group
ether
SMILES string
C1[C@@H]2OC(CC3=N[C@H]4[C@@H](Cc5ccccc45)O3)=N[C@H]2c6ccccc16
InChI
1S/C21H18N2O2/c1-3-7-14-12(5-1)9-16-20(14)22-18(24-16)11-19-23-21-15-8-4-2-6-13(15)10-17(21)25-19/h1-8,16-17,20-21H,9-11H2/t16-,17-,20+,21+/m0/s1
InChI key
BDHSVQLSNIGJNC-ZCLUNYJNSA-N
Application
[3aR-[2(3′aR*,8′aS*),3′aβ,8′aβ]]-(+)-2,2′-Methylenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] is a C2 symmetric chiral ligand based on bis(oxazoline) moiety, which can be used in enantioselective catalysis. It easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals. Copper complex of this chiral ligand can be utilized as a reusable catalyst in the cyclopropanation reaction between styrene and ethyl diazoacetate.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Articles
BOX ligand complex enhances catalytic enantioselective aziridination of styrene, with phenyl substituents proving superior over t-Bu groups.
C 2-symmetric chiral bis (oxazoline) ligands in asymmetric catalysis
Desimoni G, et al.
Chemical Reviews, 106(9), 3561-3651 (2006)
Pfaltz, A.
Accounts of Chemical Research, 26, 339-339 (1993)
Bolm, C.
Angewandte Chemie (International Edition in English), 30, 542-542 (1991)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 464155-500MG | 04061833055250 |
