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A propos de cet article
Formule linéaire :
2-(C2H5HgS)C6H4CO2Na
Numéro CAS:
Poids moléculaire :
404.81
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8169555
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pharmaceutical primary standard
API family
thimerosal
manufacturer/tradename
USP
mp
234-237 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
[Na+].CC[Hg]Sc1ccccc1C([O-])=O
InChI
1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
InChI key
RTKIYNMVFMVABJ-UHFFFAOYSA-L
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Thimerosal USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Thimerosal Tincture
- Thimerosal Topical Aerosol®
- Thimerosal Topical Solution
Biochem/physiol Actions
Le thimérosal est un réactif oxydant les groupements sulfhydryle (thiol) qui est capable d'inhiber de multiples protéines et enzymes dépendantes de groupements sulfhydryle telles que la méthionine synthase dépendante de la PI3-kinase, les récepteurs transporteurs du glutamate et les ATPases dépendantes de Na++K+.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
Legal Information
Aerosol is a registered trademark of Cytec Technology Corp.
Disclaimer
As part of the corporationglobal plan to support the Minamata Convention in eliminatingmercury-containing compounds, as of January 2021 customers will be required toprovide an End-Use Declaration. The sales of thimerosal will be restricted forapproved applications only, such as preservative in vaccine manufacturing,preservative in eye cosmetics, research use within academia (excludingpreservation intent) and as reference material only. The product is notintended for use as a biocide under global biocide regulations, including butnot limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act ,European Biocidal Products Regulation, Canada’s Pest Management RegulatoryAgency, Turkey’s Biocidal Products Regulation,Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR)and others.
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
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Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
target_organs
Kidney
Classe de stockage
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Xiaoling Li et al.
Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 452-465 (2014-03-29)
Thimerosal is a vaccine antimicrobial preservative which has long been suspected an iatrogenic factor possibly contributing to neurodevelopmental disorders including autism. The association between infant vaccine thimerosal exposure and autism remains an open question. Although thimerosal has been removed from
David A Geier et al.
Biological trace element research, 163(1-2), 28-38 (2014-11-11)
Thimerosal is an organic mercury (Hg)-containing compound (49.55 % Hg by weight) historically added to many multi-dose vials of vaccine as a preservative. A hypothesis testing case-control study evaluated automated medical records in the Vaccine Safety Datalink (VSD) for organic Hg
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 1659000-500MG | 04061838748775 |