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1173100

USP

Desmethoxycurcumin

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

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A propos de cet article

Formule empirique (notation de Hill) :
C20H18O5
Numéro CAS:
Poids moléculaire :
338.35
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

curcumin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O(C)c1c(ccc(c1)\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)O)O

InChI

1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+

InChI key

HJTVQHVGMGKONQ-LUZURFALSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Desmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Curcuminoids Tablets
  • Curcuminoids
  • Powdered Turmeric Extract
  • Powdered Turmeric
  • Turmeric

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Mei-Chun Kou et al.
Molecular nutrition & food research, 57(9), 1598-1610 (2013-02-07)
Curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) have been demonstrated as having antioxidant, anticarcinogenic, and hypocholesterolemic activities. We report the diverse antiatherogenic effects and mechanisms of curcuminoids. We found that CUR was the most potent antioxidant against copper-mediated LDL oxidation
Kun Wang et al.
Current drug metabolism, 14(7), 791-806 (2013-08-14)
Curcuminoids are safe natural yellow pigments used as food coloring agents and traditional drugs with a variety of biological functions such as antitumor, anti-inflammatory and antioxidant activities. Poor oral bioavailability and the low plasma concentration of curcuminoids limited their clinical
Yanyu Xiao et al.
Journal of agricultural and food chemistry, 61(15), 3654-3660 (2013-03-05)
Curcuminoid, a dietary polyphenolic compound, has poor water solubility and low bioavailability following oral administration. The aim of this study was to develop a formulation of curcuminoid-loaded microemulsion (Cur-ME) to improve its oral bioavailability. The optimized Cur-ME formulation was prepared



Numéro d'article de commerce international

RéférenceGTIN
1173100-30MG04061833859728