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P9158

Pyridoxamine dihydrochloride

Name: Pyridoxamine dihydrochloride
Brand: SIGMA

BioReagent, suitable for cell culture

Synonyme(s) :

4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :

C₈H₁₂N₂O₂ · 2HCl

Numéro CAS:

524-36-7

Poids moléculaire :

241.11

UNSPSC Code:

12352205

NACRES:

NA.75

PubChem Substance ID:

24899015

EC Number:

208-357-6

Beilstein/REAXYS Number:

3632748

MDL number:

MFCD00012808

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Propriétés

biological source

synthetic (organic)

Quality Level

200

product line

BioReagent

assay

≥98%

form

powder

mol wt

M_w 241.11 g/mol

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

224-226 °C (dec.) (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Cc1ncc(CO)c(CN)c1O

InChI

1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H

InChI key

HNWCOANXZNKMLR-UHFFFAOYSA-N

Description

Application

Use in mammalian cell culture as an alternative to pyridoxine or pyridoxal. Vitamin B6 is a required component of cell culture media. Historically, media have been supplemented with vitamin B6 in the aldehyde form, pyridoxal. While this is a biologically active form of vitamin B6, it is unstable in liquid media. When cells are able to utilize either pyridoxine and/or pyridoxamine, they are preferred supplement versus pyridoxal. A number of classical media are now offered with a choice between pyridoxal and pyridoxine as the vitamin A source.

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Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Articles

Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model.

Petia Kovatcheva-Datchary et al.

Cell reports, 26(13), 3772-3783 (2019-03-28)

The gut microbiota can modulate human metabolism through interactions with macronutrients. However, microbiota-diet-host interactions are difficult to study because bacteria interact in complex food webs in concert with the host, and many of the bacteria are not yet characterized. To

Numéro d'article de commerce international

Référence	GTIN
P9158-1G	04061834402534