H4036
L-histidine monohydrochloride monohydrate
Synonyme(s) :
Acide L-α-amino-β-(4-imidazolyl)propionique monohydrochloride
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A propos de cet article
Formule empirique (notation de Hill) :
C6H9N3O2 · HCl · H2O
Numéro CAS:
Poids moléculaire :
209.63
UNSPSC Code:
12352209
NACRES:
NA.26
eCl@ss:
32160406
MDL number:
Beilstein/REAXYS Number:
4168261
Service technique
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Laissez-nous vous aiderbiological source
non-animal source
assay
≥98.5%
form
powder
manufacturer/tradename
Ajinomoto
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, heavy metals, residual solvents, tested
mp
254 °C (dec.) (lit.)
solubility
H2O: 50 mg/mL
application(s)
pharmaceutical (small molecule)
foreign activity
cytotoxicity, tested
SMILES string
O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI
1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI key
CMXXUDSWGMGYLZ-XRIGFGBMSA-N
General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.
Application
L-Histidine, an essential amino acid. It is used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Histidine monohydrochloride monohydrate is a modified version of L-Histidine with improved solubility.
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Contenu apparenté
Bakul Bhatnagar et al.
The journal of physical chemistry. B, 123(27), 5690-5699 (2019-07-02)
Protein/ice interactions are investigated by a novel method based on measuring the characteristic features of X-ray diffraction (XRD) patterns of hexagonal ice (Ih). Aqueous solutions of four proteins and other solutes are studied using high-resolution synchrotron XRD. Two pharmaceutical proteins
Martin Maldonado et al.
Neurochemistry international, 85-86, 31-39 (2015-05-06)
The effect of reserpine on histamine (HA) and tele-methylhistamine (N(τ)-MHA) in hypothalamus and cortex of rats was analyzed and compared to catecholamines. IP injection of reserpine (5 mg/kg) confirmed the effectiveness of reserpine treatment on noradrenaline and dopamine levels. Our in-vitro
Verena Saller et al.
Journal of pharmaceutical sciences, 104(4), 1440-1450 (2015-01-22)
In a typical manufacturing setup for biopharmaceutical drug products, the fill and dosing pump is placed after the final sterile filtration unit in order to ensure adequate dispensing accuracy and avoid backpressure peaks. Given the sensitivity of protein molecules, peristaltic
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| H4036-25KG | 04061834415480 |
| H4036-100G | 04061834353836 |
| H4036-10KG | 04061834415466 |
| H4036-1KG | 04061833794548 |