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E6635

Acide éthylènediaminetétraacétique disodium salt dihydrate

Name: Acide éthylènediaminetétraacétique disodium salt dihydrate
Brand: SIGMA

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

Synonyme(s) :

EDTA disodium salt, EDTA-Na₂, Edétate disodium salt dihydrate, Sequestrene Na₂, Édathamil, Éthylènediaminetétraacétate disodique dihydrate

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A propos de cet article

Formule empirique (notation de Hill) :

C₁₀H₁₄N₂Na₂O₈ · 2H₂O

Numéro CAS:

6381-92-6

Poids moléculaire :

372.24

NACRES:

NA.77

PubChem Substance ID:

24894632

UNSPSC Code:

12352107

EC Number:

205-358-3

Beilstein/REAXYS Number:

3900609

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Propriétés

grade

Sigma Grade

assay

98.5-101.5%

form

powder

reaction suitability

reagent type: chelator

technique(s)

cell culture | plant: suitable

mp

248 °C (dec.) (lit.)

solubility

H₂O: soluble, clear, colorless

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

Description

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Application

Chélateur de cations divalents. Inhibe les enzymes dont l′activité exige des cations divalents, comme les métalloprotéinases.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten. It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.