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C7559

Chloroforme

Name: Chloroforme
Brand: SIGMA

≥99%, PCR Reagent, contains amylenes as stabilizer

Synonyme(s) :

Trichlorométhane, Trichlorure de méthylidyne

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A propos de cet article

Formule empirique (notation de Hill) :

CHCl₃

Numéro CAS:

67-66-3

Poids moléculaire :

119.38

UNSPSC Code:

12191502

NACRES:

NA.28

PubChem Substance ID:

24892970

EC Number:

200-663-8

Beilstein/REAXYS Number:

1731042

MDL number:

MFCD00000826

Assay:

≥99%

Technique(s):

PCR: suitable

Bp:

60.5-61.5 °C (lit.)

Vapor pressure:

160 mmHg ( 20 °C)

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Propriétés

vapor density

4.1 (vs air)

Quality Level

200

vapor pressure

160 mmHg ( 20 °C)

assay

≥99%

form

liquid

contains

amylenes as stabilizer

packaging

vial of 1.5 mL

technique(s)

PCR: suitable

color

colorless

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

foreign activity

DNase, RNase, none detected

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

General description

Chloroform is used in pharmaceutical preparations as an anesthetic and as an additive. It is now mainly used as an organic solvent. Chloroform is produced by anthropogenic and natural sources. This abundant halocarbon in the atmosphere is found in ground and surface water sources.

Application

Chloroform has been used in phenol-chloroform extraction to find its ability to purify nucleic acids from blood culture fluids. It has also been used in RNA extraction/isolation and purification.

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pictograms

GHS06,GHS08

signalword

Danger

hcodes

H302,H315,H319,H331,H336,H351,H361d,H372,H412

pcodes

P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

ppe

Eyeshields, Faceshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number

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Protocoles

Amplification of DNA Using Jumpstart™ REDTaq^® DNA Polymerase (D8187)

Protocol using antibody mediated hot start polymerase with a red dye for easy gel loading. Method has short activation period (<1min), and results in higher yields and more specificity over standard PCR methods.

Kidney

Encyclopedia of Toxicology (2014)

LKB1 couples glucose metabolism to insulin secretion in mice.

Accalia Fu et al.

Diabetologia, 58(7), 1513-1522 (2015-04-16)

Precise regulation of insulin secretion by the pancreatic beta cell is essential for the maintenance of glucose homeostasis. Insulin secretory activity is initiated by the stepwise breakdown of ambient glucose to increase cellular ATP via glycolysis and mitochondrial respiration. Knockout

Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study.

Mette Bohl et al.

The American journal of clinical nutrition, 101(4), 870-878 (2015-04-04)

Abdominal obesity and exaggerated postprandial lipemia are independent risk factors for cardiovascular disease (CVD) and mortality, and both are affected by dietary behavior. We investigated whether dietary supplementation with whey protein and medium-chain saturated fatty acids (MC-SFAs) improved postprandial lipid

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Numéro d'article de commerce international

Référence	GTIN
C7559-5VL	04061833512944