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MilliporeSigma

A6582

Antifoam A concentrate

active silicone polymer 100%

Synonyme(s) :

Antifoam agent, Antifoam solution, Foam control agent

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A propos de cet article

NACRES:
NA.85
UNSPSC Code:
12161901
Service technique
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Quality Level

form

emulsion (aqueous)

technique(s)

cell culture | hybridoma: suitable, microbiological culture: suitable

density

0.97 g/mL at 25 °C

application(s)

microbiology

storage temp.

room temp

suitability

(Mammalian (suspension)), bacteria (fermentation)

General description

Antifoam A is a silicone-based product used to prevent or minimize foaming in both microbial fermentation systems and mammalian suspension cultures. Control of foaming minimizes damage to the cells, resulting in increased protein/antibody production. Extremely effective for aqueous and non-aqueous systems. Effective at concentrations in the 1-50ppm range.

Application

Antifoam A concentrate has been used:
  • in bioreactor culture for Staphylococcal enterotoxin C (SEC) production.
  • to prevent foam formation during the aerobic treatment of sludge.
  • to study the impact of surface tension on bioaerosol generation during bubbling.

Features and Benefits

  • Molecular biology grade and tested for use in bacterial fermentation.
  • Extremely effective foam suppressor for aqueous and non-aqueous systems.
  • Made of 100% active silicone polymer, free of emulsifiers.
  • Typically, effective at 1-100 ppm.
  • Product will be stable in the pH range of 5 to 9.
  • Can be directly added to a fermentation medium but it is not recommended that it be pumped to a fermenter on an as-needed basis.

Preparation Note

Antifoam A can be pre-diluted with 3-10 parts of aqueous propylene glycol or non-aqueous vegetable oil with slow mixing.

Other Notes

Antifoam A is a 100% active silicon polymer containing no non-ionic emulsifiers .


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pictograms

Environment

Classe de stockage

10 - Combustible liquids

wgk

WGK 3

flash_point_f

>213.8 °F - closed cup

flash_point_c

> 101 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - PBT - vPvB



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M Schlömann et al.
Journal of bacteriology, 172(9), 5119-5129 (1990-09-01)
Enzymatic conversion of 4-fluorocatechol in the simultaneous presence of partially purified preparations of catechol 1,2-dioxygenase from Pseudomonas cepacia and muconate cycloisomerase from Alcaligenes eutrophus 335 yielded a product that was unambiguously identified as (+)-4-fluoromuconolactone [(+)-4-carboxymethyl-4-fluoro-but-2-en-4-olide]. This compound was shown to
F P Ernani et al.
Infection and immunity, 61(6), 2596-2601 (1993-06-01)
Substantial evidence indicates that molecules released by infectious organisms affect virulence and influence immunity to infection. The characterization of extracellular molecules and their mechanism of release is therefore critical to understanding host-parasite relationships. The cestode parasite Mesocestoides corti is known
Experience with a perfo-suction system for the recovery of schistosomes from laboratory rodents
T. F. H. G. Jackson, C. D. Dettman, et al.
Laboratory Animal Science, 16, 65-67 (1982)



Numéro d'article de commerce international

RéférenceGTIN
A6582-100G04061833382516