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MilliporeSigma

89510

Poly(éthylène glycol)

greener alternative

BioUltra, 8,000

Synonyme(s) :

PEG

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A propos de cet article

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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Quality Level

product line

BioUltra

form

solid

mol wt

Mr 7000-9000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test, ≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

61-64 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.09, λ: 280 nm Amax: 0.03

greener alternative category

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Poly(ethylene glycol) (PEG) is a polymer of ethylene glycol units and is hydrophilic in nature. PEG has high hydration capacity and is structurally flexible. PEG has advantage as a drug conjugate due to biocompatibility and nonexistence of steric hindrances in its structure.

Application

Poly(ethylene glycol) has been used:
  • in the transformation buffer in yeast
  • as a constituent of dengue virus isolation buffer
  • for concentration of lentivirus particles
  • in the crystallization of herpesvirus nuclear egress complex (NEC)

Biochem/physiol Actions

The Food and Drug Administration (FDA) approved PEG as drug conjugates, is nonimmunogenic and safe. PEG is widely used as a reagent in biochemistry and molecular biology experiments. PEG conjugation improves solubility and dissolution of diabetes drug, Gliclazide. It is used in carbon nanotube functionalization. The presence of PEG 8000 in the tannin tree foliage improves metabolisable energy (ME) content and gas production.


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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Contenu apparenté

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.


Characterisation of gliclazide-PEG 8000 solid dispersions
Biswal S, et al.
Tropical Journal of Pharmaceutical Research, 8(5) (2009)
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions
Zhang C, et al.
Scientific Reports, 7(1), 44708-44708 (2017)
A simple, inexpensive, robust and sensitive dot-blot assay for equal detection of the nonstructural-1 glycoprotein of all dengue virus serotypes
Falconar AK and Romero-Vivas CM
Virology Journal, 10(1), 126-126 (2013)



Numéro d'article de commerce international

RéférenceGTIN
H16205-25G04061831826890
H16205-100G04061833670354
89510-1KG-F04061835442225
89510-250G-F04061835541843