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30170

L-Cysteic acid monohydrate

≥99.0% (T), suitable for LC/MS

Synonyme(s) :

(R)-2-Amino-3-sulfopropionic acid

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A propos de cet article

Formule linéaire :
HO3SCH2CH(NH2)CO2H·H2O
Numéro CAS:
Poids moléculaire :
187.17
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
3714036
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Nom du produit

L-Cysteic acid monohydrate, ≥99.0% (T)

Quality Level

assay

≥99.0% (T)

form

powder or crystals

optical activity

[α]20/D +7.5±0.5°, c = 5% in H2O

technique(s)

LC/MS: suitable

color

white to faint yellow

mp

267 °C (dec.) (lit.)

solubility

H2O: soluble

application(s)

peptide synthesis

SMILES string

[H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O

InChI

1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1

InChI key

PCPIXZZGBZWHJO-DKWTVANSSA-N

Application

Internal standard for amino acid analysis.

Biochem/physiol Actions

L-Cysteic acid is a sulfur containing aspartate analogue that may be used as a competitive inhibitor of the bacterial aspartate:alanine antiporter (AspT) exchange of aspartate and in other aspartate biological systems. L-Cysteic acid is used in monomeric surfactant development.
L-cysteic acid is an oxidation product of L-cysteine. L-Cysteic acid, an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain, such as those that bind to cysteine sulfinic acid receptors. L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors (mGluRs).


Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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B Meldrum
Epilepsia, 25 Suppl 2, S140-S149 (1984-01-01)
Amino acids provide the most universal and important inhibitory (gamma-aminobutyric acid (GABA), glycine) and excitatory (glutamate, aspartate, cysteic acid, cysteine sulphinic acid) neurotransmitters in the brain. An anticonvulsant action may be produced (1) by enhancing inhibitory (GABAergic) processes, and (2)
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
Qi Shi et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 131-142 (2003-03-22)
Moderate hyperhomocysteinemia is associated with several diseases, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, and spina bifida. However, the mechanisms for their pathogenesis are unknown but could involve the interaction of homocysteine or its metabolites with molecular targets such



Numéro d'article de commerce international

RéférenceGTIN
30170-10G04061826665510
30170-50G04061832719054