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137279

L-Arginine

Name: <SC>L</SC>-Arginine
Brand: SIGMA

EMPROVE^® EXPERT, EP, USP

Synonyme(s) :

Acide (S)-2-amino-5-guanidinopentanoïque

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A propos de cet article

Formule linéaire :

H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H

Numéro CAS:

74-79-3

Poids moléculaire :

174.20

UNSPSC Code:

12352209

NACRES:

NA.26

eCl@ss:

32160406

MDL number:

MFCD00002635

Beilstein/REAXYS Number:

1725413

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Propriétés

biological source

non-animal source

Quality Level

500

agency

EP, USP

product line

EMPROVE^® EXPERT

assay

>98.5%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, residual solvents

mp

222 °C (dec.) (lit.)

solubility

H₂O: 100 mg/mL

suitability

suitable for manufacturing use

application(s)

pharmaceutical (small molecule)

SMILES string

N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

InChI key

ODKSFYDXXFIFQN-BYPYZUCNSA-N

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

Description

General description

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our Emprove^® Program, our raw materials are offered with Emprove^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Arginine is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Arginine monohydrochloride is a modified version of L-Arginine with improved solubility.

Biochem/physiol Actions

Substrat de l′oxyde nitrique synthase qui est converti en citrulline et oxyde nitrique (NO). Induit la libération d′insuline par un mécanisme dépendant de l′oxyde nitrique.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c