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PHR1418

Acide succinique

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Acide butanedioïque

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A propos de cet article

Formule linéaire :
HOOCCH2CH2COOH
Numéro CAS:
Poids moléculaire :
118.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-740-4
Beilstein/REAXYS Number:
1754069
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1623411

API family

succinic acid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

General description

Succinic acid is a dicarboxylic acid, which is used primarily as an acidity regulator in the food and beverage industry. Pharmaceutically, it is usually used as a conjugate feeder acid to form succinate salt and as an excipient.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Succinic acid may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2952 in the slot below. This is an example certificate only and may not be the lot that you receive.


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Protocoles

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Articles

A new RP-HPLC method is proposed for the determination of organic acids in 100% aqueous mobile phase using an Ascentis® Express AQ-C18 column


Optimization and validation of an HPLC-photodiode array detector method for determination of organic acids in vinegar
Zong Y, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(2), 422-430 (2015)
Determination of lactic, acetic, succinic, and citric acids in table olives by HPLC/UV
Cunha SC, et al.
Journal of Liquid Chromatography and Related Technologies, 24(7), 1029-1038 (2001)
Food additives data book
Food additives data book, 56, 66-69 (2003)



Numéro d'article de commerce international

RéférenceGTIN
PHR1418-1G04061834416357