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PHR1123

Isopropyl myristate

Name: Isopropyl myristate
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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A propos de cet article

Formule linéaire :

CH₃(CH₂)₁₂COOCH(CH₃)₂

Numéro CAS:

110-27-0

Poids moléculaire :

270.45

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823144

EC Number:

203-751-4

Beilstein/REAXYS Number:

1781127

MDL number:

MFCD00008982

eCl@ss:

39022421

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Propriétés

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. I0750000, traceable to USP 1350400

API family

isopropyl myristate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

Description

General description

Isopropyl myristate is an ester of isopropyl alcohol myristic acid. It is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It also finds applications as a flavoring agent in the food industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7001 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Classe de stockage

10 - Combustible liquids

wgk

awg

flash_point_f

>302.0 °F

flash_point_c

> 150 °C

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

CRC Handbook of Food, Drug, and Cosmetic Excipients (1992)

Investigation of microemulsion microstructures and their relationship to transdermal permeation of model drugs: ketoprofen, lidocaine, and caffeine.

Ji Zhang et al.

International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)

In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant

Preparation of high solubilizable microemulsion of naproxen and its solubilization mechanism.

Qingping Tian et al.

International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)

To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and

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Numéro d'article de commerce international

Référence	GTIN
PHR1123-1G	04061835233175