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91275

Propionyl-L-carnitine

analytical standard

Synonyme(s) :

(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine

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A propos de cet article

Formule empirique (notation de Hill) :
C10H19NO4
Numéro CAS:
Poids moléculaire :
217.26
UNSPSC Code:
41116107
NACRES:
NB.21
MDL number:
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grade

analytical standard

Quality Level

assay

≥94.0% (HPLC)

optical activity

[α]/D -24.0±2.0°, c = 0.2 in H2O

shelf life

limited shelf life, expiry date on the label

impurities

≤13% water ((calculated from elemental analysis)

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O

InChI

1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1

InChI key

UFAHZIUFPNSHSL-MRVPVSSYSA-N

General description

Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

Application

Propionyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques. It may also be used as an analytical standard in monitoring the analyte in chemical synthesis procedures and pharmaceutical formulations using a stereospecific enzyme assay and high-performance liquid chromatography technique with UV detection.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.


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Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certificats d'analyse (COA)

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Application of high-performance liquid chromatography to the analysis of propionyl-L-carnitine by a stereospecific enzyme assay
Marzo A, et al.
Journal of Chromatography A, 459, 313-317 (1988)
Determination of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivatization with 1-aminoanthracene
Longo A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 686(2), 129-139 (1996)
Quantitation of L?carnitine, acetyl?L?carnitine, propionyl?L?carnitine and their deuterated analogues by high?performance liquid chromotography tandem mass spectrometry
Tallarico C , et al.
Rapid Communications in Mass Spectrometry, 12(7), 403-409 (1998)



Numéro d'article de commerce international

RéférenceGTIN
91275-10MG04061834156994
91275-50MG04061834157007